Name : OXSR1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8963882841
| Long name | OXSR1 Primary Polyclonal Antibody |
| Also known as | OXSR1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | OXSR1 |
| Specificity | This is a highly specific antibody against OXSR1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human OXSR1 |
| Gene ID number | 9943 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Binds to and phosphorylates RELL1, NaCl, OXSR1 interacts with chloride channel proteins SLC12A6 isoform 2, OXSR1 may have a role in regulating the actin cytoskeleton, OXSR1 phosphorylated thr84 within the N-terminal regulatory domain of PAK1, RELL2 AND RELT, Replacement of thr84 with gln reduced activation of PAK1 by an active form of the small G protein CDC42, SLC12A1 and SLC12A2 but not with SLC12A4 and SLC12A7, notably sorbitol and, possibly establishing sensor/signaling modules that initiate the cellular response to environmental stress, suggesting that phosphorylation by OXSR1 modulates the G protein sensitivity of PAK, to a lesser extent, OXSR1 is a serine/threonine kinase which regulates downstream kinases in response to environmental stress such as osmotic stresses |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | OSR 1, OSR1, OXSR 1, Oxidative stress responsive 1, Oxidative stress responsive 1 protein, Serine/threonine protein kinase OSR1, KIAA1101 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | OXSR1 |
| Short name | OXSR1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | oxidative-stress responsive 1 (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cytoplasm, OSR1, OXSR1 and IDBG-25753 and ENSG00000172939 and 9943, OXSR1 and IDBG-644304 and ENSBTAG00000014927 and 526949, Oxsr1 and IDBG-204530 and ENSMUSG00000036737 and 108737, this GO :0000287 and magnesium ion binding and molecular function this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004702 and receptor signaling protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0016772 and transferase activity, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004702: receptor signaling protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004672: protein kinase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004702: receptor signaling protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups, transferring phosphorus-containing groups and molecular function this GO :0018107 and peptidyl-threonine phosphorylation and biological process this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0035556 and intracellular signal transduction and biological process this GO :0070062 and extracellular vesicular exosome and cellular component this GO :0071476 and cellular hypotonic response and biological process this GO :1901017 and negative regulation of potassium ion transmembrane transporter activity and biological process this GO :1901380 and negative regulation of potassium ion transmembrane transport and biological process this GO :2000681 and negative regulation of rubidium ion transport and biological process this GO :2000687 and negative regulation of rubidium ion transmembrane transporter activity and biological process, oxidative-stress responsive 1 |
| Identity | 8508 |
| Gene | OXSR1 |
| Long gene name | oxidative stress responsive 1 |
| Synonyms gene | OSR1 |
| Synonyms gene name | oxidative-stress responsive 1 |
| Synonyms | KIAA1101 |
| Locus | 3p22, 2 |
| Discovery year | 1999-05-06 |
| GenBank acession | AB017642 |
| Entrez gene record | 9943 |
| Pubmed identfication | 10083736 |
| RefSeq identity | NM_005109 |
| Havana BLAST/BLAT | OTTHUMG00000131084 |