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p-NANOG Antibody (pS71)

p-NANOG Antibody (pS71) size: 0.4 ml 406

Supplier NJS POLY
Price 406
Size 0.4 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenp-NANOG (pS71)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications DB, ELISA, IF
Recommended dilutionsDot blot: 1:500, Immunofluorescence: 1:10-1:50
NotesTitration of the p-NANOG antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis p-NANOG antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q9H9S0
PurityAntigen affinity
Description It binds optimally to the DNA consensus sequence 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3', It imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages, NANOG acts as a transcriptional activator or repressor, This protein blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes, When overexpressed, this protein promotes cells to enter into S phase and proliferation, NANOG is a transcription regulator involved in inner cell mass and embryonic stem (ES) cels proliferation and self-renewal
ImmunogenThis p-NANOG antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS71 of human Nanog
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the p-NANOG antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetp-NANOG (pS71)
Short namep-NANOG Antibody (pS71)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep-NANOG (Antibody to) (pS71)
Alternative techniqueantibodies
Identity 20857
Gene NANOG
Long gene name Nanog homeobox
Synonyms FLJ12581 FLJ40451
Locus 12p13, 31
Discovery year 2003-09-10
GenBank acession AB093576
Entrez gene record 79923
Pubmed identfication 12787505 12787504
RefSeq identity NM_024865
Classification NKL subclass homeoboxes and pseudogenes
Havana BLAST/BLAT OTTHUMG00000166019

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