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P-Selectin Antibody

P-Selectin Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenP-Selectin
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the P-Selectin antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis CD62P antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P16109
PurityAntigen affinity
Description Expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, GRMP, In quiescent platelet, P-Selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury, P-selectin plays an essential role in the initial recruitment of leukocytes(white blood cells) to the site of injury during inflammation, Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin, The gene is mapped on 1q24, also called CD62P, and GMP140 is a 140-kD adhesion molecule, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes, the protein is located on the inner wall of alpha-granules, 2, P-Selectin
ImmunogenAn amino acid sequence from the N-terminus of human P-Selectin (KAYSWNISRKYCQNRYTD) was used as the immunogen for this P-Selectin antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the P-Selectin antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetP-Selectin
Short nameP-Selectin Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameP-Selectin (Antibody to)
Alternative techniqueantibodies
Identity 18966
Gene CSAD
Long gene name cysteine sulfinic acid decarboxylase
Synonyms PCAP CSD
Synonyms name P-selectin cytoplasmic tail-associated protein
Locus 12q13, 13
Discovery year 2002-07-25
GenBank acession AB044561
Entrez gene record 51380
Pubmed identfication 15489334
RefSeq identity NM_015989
Havana BLAST/BLAT OTTHUMG00000048076

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