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P100 (19AT953.286.93) Monoclonal Antibody

P100 (19AT953.286.93) Monoclonal Antibody size: 0.1ml 211

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 211
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name286, 93) Monoclonal Antibody, P100 (19AT953
Also known as286, 93) Monoclonal Antibody, P100 (19AT953
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenP100
SpecificityThis is a highly specific antibody against P100
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityMonoclonal
Clone number19AT953, 93, 286
SourceThis monoclonal antibody is generated from mice immunized with a collection of antigenic peptides from different regions of P100
Gene ID number22974
Swiss ProtQ9ULW0
Tested ApplicationsWB
Recommended dilutionsWB(1:1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation (PubMed:18663142, At the onset of mitosis, GOLGA2 interacts with importin-alpha, Mediates AURKA localization to spindle microtubules (PubMed:18663142, PubMed:19208764), PubMed:19208764), Required for chromatin and/or kinetochore dependent microtubule nucleation, Required for normal assembly of microtubules during apoptosis, TPX2 is inactivated upon binding to importin-alpha (PubMed:26165940), allowing TPX2 to activates AURKA kinase and stimulates local microtubule nucleation (PubMed:26165940), liberating TPX2 from importin-alpha, Spindle assembly factor required for normal assembly of mitotic spindles
Purification method This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS, 09% (W/V) sodium azide, Purified monoclonal antibody supplied in PBS with 0
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names C20orf1, C20orf2, DIL-2, Differentially expressed in cancerous and non-cancerous lung cells 2, FLS353, GD:C20orf1, HCA519, HCTP4, Hepatocellular carcinoma-associated antigen 519, Hepatocellular carcinoma-associated antigen 90, Protein fls353, REPP86, Restricted expression proliferation-associated protein 100, TPX2, Targeting protein for Xklp2, p100, DIL2
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
About Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones
Gene target286, 93) Monoclonal, P100 (19AT953
Short name286, 93) Monoclonal Antibody, P100 (19AT953
Technique Monoclonals or monoclonal antibodies, antibodies against human proteins, antibodies for, Antibody
Alternative name286, 93) monoclonal (Antibody to), P100 (19AT953
Alternative techniqueantibodies
Identity 30646
Gene SND1
Long gene name staphylococcal nuclease and tudor domain containing 1
Synonyms TDRD11 p100
Synonyms name p100 EBNA2 co-activator Tudor-SN
Locus 7q32, 1
Discovery year 2006-12-19
Entrez gene record 27044
Pubmed identfication 7651391 9003410 12819296
RefSeq identity NM_014390
Classification Tudor domain containing
Havana BLAST/BLAT OTTHUMG00000157560

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