Filters

P105 RB(Ser612) Antibody, Cy7 Conjugated

P105 RB(Ser612) Antibody, Cy7 Conjugated size: 0.1ml 368

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 368
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Cy7 Conjugated, P105 RB(Ser612) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationCy7
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenP105 RB Ser612
SpecificityThis is a highly specific antibody against P105 RB Ser612
ModificationPhosphorylation
Modification siteSer612
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human Retinoblastoma associated protein around the phosphorylation site of Ser612
Gene ID number5925
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background ATF2, Aberrations in the Rb gene have been implicated in cancers of breast, Elf1 and cAbl, It forms a complex with SV40 large T antigen, PU1, Rb is phosphorylated on serine and threonine, Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth, This ability of Rb to alter transcription is regulated by phosphorylation catalyzed by the cyclin dependent protein kinases (cdks), UBF, adenovirus E1A, and human papilloma virus 16E, and leukemia, but not on tyrosine residues, colon, kidney, nasopharynx, prostate, Rb is a tumor suppressor gene which functions as a negative regulator of the cell cycle by interacting with transcription factors including E2F1
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission743nm/767nm
Synonyms LYT-10 p52 p105 NF-kB2 p49/p100
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
ConjugatedThese antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths
Gene targetP105 RB(Ser612) Conjugated
Short name Conjugated, P105 RB(Ser612) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy7
Alternative name cyanine 7 coupled, P105 RB(Ser612) (Antibody to)
Alternative techniqueantibodies
Identity 7795
Gene NFKB2
Long gene name nuclear factor kappa B subunit 2
Synonyms gene name nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Locus 10q24, 32
Discovery year 1991-11-14
GenBank acession X61498
Entrez gene record 4791
Pubmed identfication 1876189
Classification Ankyrin repeat domain containing NF-kappa B complex subunits
Havana BLAST/BLAT OTTHUMG00000018962

Similar products

Subscribe to our Newsletter