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p107 Antibody

p107 Antibody size: 0.1ml 263

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 263
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namep107 Primary Polyclonal Antibody
Also known asp107 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target Antigenp107
SpecificityThis is a highly specific antibody against p107
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p107/RBL1
Gene ID number5933
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, Due to the sequence and biochemical similarities with the RB1 protein, In addition, Two transcript variants encoding different isoforms have been found for this gene, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters, it is thought that the protein encoded by this gene may also be a tumor suppressor, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein, p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CP107, Cellular protein 107, Cellular protein p107, MGC40006, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, Retinoblastoma-like protein 1, p107, retinoblastoma-like 1 p107, 107 kDa retinoblastoma-associated protein
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetp107
Short namep107 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep107 (Antibody to)
Alternative techniqueantibodies
Identity 9893
Gene RBL1
Long gene name RB transcriptional corepressor like 1
Synonyms gene name retinoblastoma-like 1
Synonyms p107 cp107 PRB1
Locus 20q11, 23
Discovery year 1994-01-07
GenBank acession L14812
Entrez gene record 5933
Pubmed identfication 1833063
RefSeq identity NM_002895
Havana BLAST/BLAT OTTHUMG00000032406

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