Name : p107 Antibody, ALEXA FLUOR 594
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN6246008059
| Long name | ALEXA FLUOR 594 Conjugated, p107 Polyclonal Antibody |
| Also known as | Anti-p107 PAb ALEXA FLUOR 594 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 594, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | p107 |
| Specificity | This is a highly specific antibody against p107 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p107/RBL1 |
| Gene ID Number | 5933 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, Due to the sequence and biochemical similarities with the RB1 protein, In addition, Two transcript variants encoding different isoforms have been found for this gene, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters, it is thought that the protein encoded by this gene may also be a tumor suppressor, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein, p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 590nm/617nm |
| Synonyms | p107 cp107 PRB1 |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | 594, ALEXA FLUOR®, Alexa Fluor |
| Conjugated | Alexa conjugate 1 |
| Gene target | p107 |
| Short name | p107 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 594 |
| Alternative name | ALEXA FLUOR 594, p107 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 9893 |
| Gene | RBL1 |
| Long gene name | RB transcriptional corepressor like 1 |
| Synonyms gene name | retinoblastoma-like 1 |
| Locus | 20q11, 23 |
| Discovery year | 1994-01-07 |
| GenBank acession | L14812 |
| Entrez gene record | 5933 |
| Pubmed identfication | 1833063 |
| RefSeq identity | NM_002895 |
| Havana BLAST/BLAT | OTTHUMG00000032406 |