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p107 Antibody, Biotin Conjugated

p107 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, p107 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenp107
SpecificityThis is a highly specific antibody against p107
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human p107/RBL1
Gene ID number5933
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, Due to the sequence and biochemical similarities with the RB1 protein, In addition, Two transcript variants encoding different isoforms have been found for this gene, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters, it is thought that the protein encoded by this gene may also be a tumor suppressor, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein, p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms CP107, Cellular protein 107, Cellular protein p107, MGC40006, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, Retinoblastoma-like protein 1, p107, retinoblastoma-like 1 p107, 107 kDa retinoblastoma-associated protein
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetp107 Conjugated
Short name Conjugated, p107 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, p107 (Antibody to)
Alternative techniqueantibodies

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