Name : p107 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN1436856166
| Long name | FITC Conjugated, p107 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | p107 |
| Specificity | This is a highly specific antibody against p107 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human p107/RBL1 |
| Gene ID number | 5933 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, Due to the sequence and biochemical similarities with the RB1 protein, In addition, Two transcript variants encoding different isoforms have been found for this gene, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters, it is thought that the protein encoded by this gene may also be a tumor suppressor, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein, p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | CP107, Cellular protein 107, Cellular protein p107, MGC40006, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, Retinoblastoma-like protein 1, p107, retinoblastoma-like 1 p107, 107 kDa retinoblastoma-associated protein |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p107 Conjugated |
| Short name | FITC Conjugated, p107 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, p107 (Antibody to) |
| Alternative technique | antibodies |