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p107(Thr369) Antibody, FITC Conjugated

p107(Thr369) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, p107(Thr369) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenp107 Thr369
SpecificityThis is a highly specific antibody against p107 Thr369
ModificationPhosphorylation
Modification siteThr369
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human p107 around the phosphorylation site of Thr369
Gene ID number5933
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Both the RB1 protein and the product of this gene can form a complex with adenovirus E1A protein and SV40 large T-antigen, Due to the sequence and biochemical similarities with the RB1 protein, In addition, Two transcript variants encoding different isoforms have been found for this gene, as it is phosphorylated in the S to M phase transition and is dephosphorylated in the G1 phase of the cell cycle, both proteins can inhibit the transcription of cell cycle genes containing E2F binding sites in their promoters, it is thought that the protein encoded by this gene may also be a tumor suppressor, with the SV40 large T-antigen binding only to the unphosphorylated form of each protein, p107 is a tumor suppressor protein that appears to be involved in cell cycle regulation
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms 107 kDa retinoblastoma-associated protein, CP107, Cellular protein 107, Cellular protein p107, MGC40006, PRB1, RBL1, RBL1_HUMAN, Retinoblastoma like protein 1, Retinoblastoma-like protein 1, p107, retinoblastoma-like 1 p107, RBL1phospho T369
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetp107(Thr369) Conjugated
Short name FITC Conjugated, p107(Thr369) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, p107(Thr369) (Antibody to)
Alternative techniqueantibodies

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