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p150 CAF1 Antibody, FITC Conjugated

p150 CAF1 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, p150 CAF1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenp150 CAF1
SpecificityThis is a highly specific antibody against p150 CAF1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human p150 CAF1
Gene ID number10036
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, Assembles histone octamers onto replicating DNA in vitro, CAF-1 performs the first step of the nucleosome assembly process, CHAF1A binds to histones H3 and H4, It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci (By similarity), The CCR4-NOT complex functions as general transcription regulation complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), a complex thought to mediate chromatin assembly in DNA replication and DNA repair, bringing newly synthesized histones H3 and H4 to replicating DNA, histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer, which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene, Core component of the CAF-1 complex
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetp150 CAF1 Conjugated
Short name FITC Conjugated, p150 CAF1 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, p150 CAF1 (Antibody to)
Alternative techniqueantibodies
Identity 14101
Gene CNOT7
Long gene name CCR4-NOT transcription complex subunit 7
Synonyms gene CAF1
Synonyms gene name CCR4-NOT transcription complex, subunit 7
Synonyms name BTG1 binding factor 1
Locus 8p22
Discovery year 2000-12-01
GenBank acession L46722
Entrez gene record 29883
Pubmed identfication 10637334 1538749 17264152
RefSeq identity NM_013354
Classification CCR4-NOT transcription complex
Havana BLAST/BLAT OTTHUMG00000096971

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