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p16INK4A Antibody (phospho-S140)

p16INK4A Antibody (phospho-S140) size: 0.08 ml 199

Supplier NJS POLY
Price 199
Size 0.08 ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration pH 7, with 0, 09% sodium azide, 4, In 1X PBS
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenp16INK4A (phospho-S140)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications ELISA, IHC, WB
Recommended dilutionsIHC (Paraffin): 1:50-1:100, Western blot: 1:1000
NotesTitration of the phospho-p16INK4A antibody may be required due to differences in protocols and secondary/substrate sensitivity
Intented useThis phospho-p16INK4A antibodyis to be used only for research purposes and not for diagnostics
Uniprot #P42771
PurityAntigen affinity
Description MDM1, The gene for this protein is frequently mutated or deleted in a wide variety of tumors, This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein, This protein acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6, a protein responsible for the degradation of p53, and is known to be an important tumor suppressor gene, and sequester, p16INK4A functions as a stabilizer of the tumor suppressor protein p53 as it can interact with
ImmunogenThis phospho-p16INK4A antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pS140 of human p16-INK4A
Storage Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, Aliquot the phospho-p16INK4A antibody and store frozen at -20 deg
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetp16INK4A (phospho-S140)
Short namep16INK4A Antibody (phospho-S140)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep16INK4A (Antibody to) (phosphorilated-S140)
Alternative techniqueantibodies

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