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P21 Antibody, Biotin Conjugated

P21 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, P21 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenP21
SpecificityThis is a highly specific antibody against P21
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range13-41/164
Subcellular location Nucleus, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human P21
Gene ID number1026
Swiss ProtP38936
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background At higher stoichiometric ratios, Binds to and inhibits cyclin-dependent kinase activity, Functions in the nuclear localization and assembly of cyclin D-CDK4 complex and promotes its kinase activity towards RB1, inhibits the kinase activity of the cyclin D-CDK4 complex, preventing phosphorylation of critical cyclin-dependent kinase substrates and blocking cell cycle progression, May be the important intermediate by which p53/TP53 mediates its role as an inhibitor of cellular proliferation in response to DNA damage
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms p21 pp21 SIIR P21 WEX9
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetP21 Conjugated
Short name Conjugated, P21 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, P21 (Antibody to)
Alternative techniqueantibodies
Identity 11616
Gene TCEAL1
Long gene name transcription elongation factor A like 1
Synonyms gene name transcription elongation factor A (SII)-like 1
Locus Xq22, 2
Discovery year 1998-09-21
GenBank acession M99701
Entrez gene record 9338
Pubmed identfication 8206389 7971997 16221301
RefSeq identity NM_004780
Classification Transcription elongation factor A like family
Havana BLAST/BLAT OTTHUMG00000022699

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