| Long name | P2RX7 Primary Polyclonal Antibody |
| Also known as | P2RX7 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | P2RX7 |
| Specificity | This is a highly specific antibody against P2RX7 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 120-170/595 |
| Subcellular location | Extracellular |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human P2RX7 |
| Gene ID number | 5027 |
| Swiss Prot | Q99572 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Could function in both fast synaptic transmission and the ATP-mediated lysis of antigen-presenting cells, Responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules, Receptor for ATP that acts as a ligand-gated ion channel |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | ATP receptor, P2RX7, P2X purinoceptor 7, P2Z receptor, Purinergic receptor, P2X7 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | P2RX7 |
| Short name | P2RX7 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | 7 (Antibody to), ligand-gated ion channel, purinergic receptor P2X |
| Alternative technique | antibodies |
| Alternative to gene target | 7, P2RX7 and IDBG-61253 and ENSG00000089041 and 5027, P2RX7 and IDBG-633042 and ENSBTAG00000008948 and 286814, P2X7, P2rx7 and IDBG-198410 and ENSMUSG00000029468 and 18439, leucine rich repeat containing receptor signaling pathway and biological process this GO :0042098 and T cell proliferation and biological process this GO :0042493 and response to drug and biological process this GO :0042803 and protein homodimerization activity and molecular function this GO :0043005 and neuron projection and cellular component this GO :0043025 and neuronal cell body and cellular component this GO :0043029 and T cell homeostasis and biological process this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043085 and positive regulation of catalytic activity and biological process this GO :0043132 and NAD transport and biological process this GO :0043195 and terminal bouton and cellular component this GO :0043234 and protein complex and cellular component this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043410 and positive regulation of MAPK cascade and biological process this GO :0044254 and multicellular organismal protein catabolic process and biological process this GO :0045087 and innate immune response and biological process this GO :0045121 and membrane raft and cellular component this GO :0045202 and synapse and cellular component this GO :0045332 and phospholipid translocation and biological process this GO :0045778 and positive regulation of ossification and biological process this GO :0045779 and negative regulation of bone resorption and biological process this GO :0045919 and positive regulation of cytolysis and biological process this GO :0046513 and ceramide biosynthetic process and biological process this GO :0046931 and pore complex assembly and biological process this GO :0048705 and skeletal system morphogenesis and biological process this GO :0048873 and homeostasis of number of cells within a tissue and biological process this GO :0050714 and positive regulation of protein secretion and biological process this GO :0050715 and positive regulation of cytokine secretion and biological process this GO :0050717 and positive regulation of interleukin-1 alpha secretion and biological process this GO :0050718 and positive regulation of interleukin-1 beta secretion and biological process this GO :0050830 and defense response to Gram-positive bacterium and biological process this GO :0051209 and release of sequestered calcium ion into cytosol and biological process this GO :0051259 and protein oli this GO merization and biological process this GO :0051495 and positive regulation of cytoskeleton organization and biological process this GO :0051592 and response to calcium ion and biological process this GO :0051602 and response to electrical stimulus and biological process this GO :0051709 and regulation of killing of cells of other organism and biological process this GO :0051899 and membrane depolarization and biological process this GO :0051901 and positive regulation of mitochondrial depolarization and biological process this GO :0055085 and transmembrane transport and biological process this GO :0070230 and positive regulation of lymphocyte apoptotic process and biological process this GO :0072593 and reactive oxygen species metabolic process and biological process this GO :0097110 and scaffold protein binding and molecular function this GO :0097190 and apoptotic signaling pathway and biological process this GO :0097191 and extrinsic apoptotic signaling pathway and biological process, ligand-gated ion channel, nuclei, scaffold protein binding, this GO :0000187 and activation of MAPK activity and biological process this GO :0000287 and magnesium ion binding and molecular function this GO :0000902 and cell morphogenesis and biological process this GO :0001530 and lipopolysaccharide binding and molecular function this GO :0001614 and purinergic nucleotide receptor activity and molecular function this GO :0001845 and pha this GO lysosome assembly and biological process this GO :0001916 and positive regulation of T cell mediated cytotoxicity and biological process this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0002028 and regulation of sodium ion transport and biological process this GO :0004872 and receptor activity and molecular function this GO :0004931 and extracellular ATP-gated cation channel activity and molecular function this GO :0005102 and receptor binding and molecular function this GO :0005216 and ion channel activity and molecular function this GO :0005507 and copper ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005639 and integral component of nuclear inner membrane and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006509 and membrane protein ectodomain proteolysis and biological process this GO :0006649 and phospholipid transfer to membrane and biological process this GO :0006811 and ion transport and biological process this GO :0006812 and cation transport and biological process this GO :0006816 and calcium ion transport and biological process this GO :0006884 and cell volume homeostasis and biological process this GO :0006900 and membrane budding and biological process this GO :0006954 and inflammatory response and biological process this GO :0007005 and mitochondrion organization and biological process this GO :0007009 and plasma membrane organization and biological process this GO :0007166 and cell surface receptor signaling pathway and biological process this GO :0008270 and zinc ion binding and molecular function this GO :0009612 and response to mechanical stimulus and biological process this GO :0009617 and response to bacterium and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0010033 and response to organic substance and biological process this GO :0010043 and response to zinc ion and biological process this GO :0010467 and gene expression and biological process this GO :0010524 and positive regulation of calcium ion transport into cytosol and biological process this GO :0012501 and programmed cell death and biological process this GO :0014049 and positive regulation of glutamate secretion and biological process this GO :0014054 and positive regulation of gamma-aminobutyric acid secretion and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0015267 and channel activity and molecular function this GO :0016020 and membrane and cellular component this GO :0016079 and synaptic vesicle exocytosis and biological process this GO :0016485 and protein processing and biological process this GO :0019228 and neuronal action potential and biological process this GO :0019233 and sensory perception of pain and biological process this GO :0019835 and cytolysis and biological process this GO :0030501 and positive regulation of bone mineralization and biological process this GO :0031594 and neuromuscular junction and cellular component this GO :0031668 and cellular response to extracellular stimulus and biological process this GO :0032059 and bleb and cellular component this GO :0032060 and bleb assembly and biological process this GO :0032308 and positive regulation of prostaglandin secretion and biological process this GO :0032496 and response to lipopolysaccharide and biological process this GO :0032731 and positive regulation of interleukin-1 beta production and biological process this GO :0032755 and positive regulation of interleukin-6 production and biological process this GO :0032963 and collagen metabolic process and biological process this GO :0033198 and response to ATP and biological process this GO :0034220 and ion transmembrane transport and biological process this GO :0034405 and response to fluid shear stress and biological process this GO :0035590 and purinergic nucleotide receptor signaling pathway and biological process this GO :0035872 and nucleotide-binding domain, this GO :0000287: magnesium ion binding, this GO :0000287: magnesium ion binding and also this GO :0001530: lipopolysaccharide binding and also this GO :0001614: purinergic nucleotide receptor activity and also this GO :0004872: receptor activity and also this GO :0004931: extracellular ATP-gated cation channel activity and also this GO :0005102: receptor binding and also this GO :0005216: ion channel activity and also this GO :0005507: copper ion binding and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0008270: zinc ion binding and also this GO :0015267: channel activity and also this GO :0042803: protein homodimerization activity and also this GO :0097110: scaffold protein binding, this GO :0001530: lipopolysaccharide binding, this GO :0001614: purinergic nucleotide receptor activity, this GO :0004872: receptor activity, this GO :0004931: extracellular ATP-gated cation channel activity, this GO :0005102: receptor binding, this GO :0005216: ion channel activity, this GO :0005507: copper ion binding, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0008270: zinc ion binding, this GO :0015267: channel activity, this GO :0042803: protein homodimerization activity, this GO :0097110: scaffold protein binding, purinergic receptor P2X |
| Identity | 8537 |
| Gene | P2RX7 |
| Long gene name | purinergic receptor P2X 7 |
| Synonyms gene name | 7 , ligand-gated ion channel, purinergic receptor P2X |
| Synonyms | P2X7 MGC20089 |
| Locus | 12q24, 31 |
| Discovery year | 1997-10-09 |
| GenBank acession | Y09561 |
| Entrez gene record | 5027 |
| Pubmed identfication | 9038151 9826911 |
| RefSeq identity | NM_002562 |
| Classification | Purinergic receptors P2X |
| Havana BLAST/BLAT | OTTHUMG00000169153 |
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