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P2X4 Antibody

P2X4 Antibody size: 0.1mg 389

Supplier NJS POLY
Price 389
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenP2X4
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applicationsWB
Recommended dilutions5-1ug/ml, Western blot: 0
Notes Titration of the P2X4 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis P2X4 antibodyis to be used only for research purposes and not for diagnostics
Uniprot #Q99571
PurityAntigen affinity
Description ATP-mediated cell death, P2RX4 is a receptor for ATP that acts as a ligand-gated ion channel, P2X4 has been implicated in the regulation of cardiac function, P2X4 in hyperactive microglia is necessary for tactile allodynia after nerve injury and is sufficient to produce tactile allodynia in normal animals, This gene belongs to the family of purinoceptors for ATP and was mapped to 12q24, This receptor is insensitive to the antagonists PPADS and suramin, also called P2X4R is a protein that in humans is encoded by the P2RX4 gene, and activating of the inflammasome in response to injury, synaptic strengthening, 32 by fluorescence in situ hybridization, Purinoceptor P2X4
ImmunogenAn amino acid sequence from the C-terminus of human P2RX4 (REKKYKYVEDYEQGLASELDQ) was used as the immunogen for this P2X4 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the P2X4 antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetP2X4
Short nameP2X4 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameP2X4 (Antibody to)
Alternative techniqueantibodies
Identity 8535
Gene P2RX4
Long gene name purinergic receptor P2X 4
Synonyms gene name 4 , ligand-gated ion channel, purinergic receptor P2X
Synonyms P2X4
Locus 12q24, 31
Discovery year 1997-10-09
GenBank acession Y07684
Entrez gene record 5025
Pubmed identfication 9016352
RefSeq identity NM_175567
Classification Purinergic receptors P2X
Havana BLAST/BLAT OTTHUMG00000169155

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