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p300 Antibody (KAT3B)

p300 Antibody (KAT3B) size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenp300 (KAT3B)
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the p300 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis p300 antibodyis to be used only for research purposes and not for diagnostics
Gene ID #2033
PurityAntigen affinity
Description In addition, It carries out its function by activating transcription, It plays an essential role in regulating cell growth and division, The gene is located on the long (q) arm of the human chromosome 22 at position 13, This protein regulates the activity of many genes in tissues throughout the body, and is important in the processes of cell proliferation and differentiation, and preventing the growth of cancerous tumors, p300 also mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein, p300 appears to be critical for normal development before and after birth, prompting cells to mature and assume specialized functions (differentiate), the protein functions as histone acetyltransferase that regulates transcription via chromatin remodeling, 2, E1A binding protein p300 is a protein that in humans is encoded by the EP300 gene
ImmunogenHuman partial recombinant protein (AA 2065-2414) was used as the immunogen for this KAT3B / p300 antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the p300 antibody can be stored for up to one month at 4oC, After reconstitution
LocalizationIntracellular
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetp300 (KAT3B)
Short namep300 Antibody (KAT3B)
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep300 (Antibody to) (KAT3B)
Alternative techniqueantibodies
Identity 3373
Gene EP300
Long gene name E1A binding protein p300
Synonyms p300 KAT3B
Synonyms name histone acetyltransferase p300
Locus 22q13, 2
Discovery year 1998-07-31
GenBank acession U01877
Entrez gene record 2033
Pubmed identfication 7523245
RefSeq identity NM_001429
Classification Zinc fingers ZZ-type Lysine acetyltransferases
Havana BLAST/BLAT OTTHUMG00000150937
Locus Specific Databases LOVD - Leiden Open Variation Database

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