Name : p300 Antibody (KAT3B)
Supplier : NJS POLY
Price :406
SKU : GEN1662373505
| Category | Antibody |
| Concentration | 2ml sterile DI water, 5mg/ml if reconstituted with 0 |
| Form | Antigen affinity purified |
| Conjugation | Unconjugated |
| Clone | Polyclonal antibody |
| Recognised antigen | p300 (KAT3B) |
| Host animal | Rabbit (Oryctolagus cuniculus) |
| Clonality | Polyclonal (rabbit origin) |
| Species reactivity | Due to limited knowledge and inability to test the antibody against all known species, Mouse (Mus musculus), Rat , we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens) |
| Tested applications | IHC-P, WB |
| Recommended dilutions | 5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0 |
| Notes | Titration of the p300 antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts |
| Intented use | This p300 antibodyis to be used only for research purposes and not for diagnostics |
| Gene ID # | 2033 |
| Purity | Antigen affinity |
| Description | In addition, It carries out its function by activating transcription, It plays an essential role in regulating cell growth and division, The gene is located on the long (q) arm of the human chromosome 22 at position 13, This protein regulates the activity of many genes in tissues throughout the body, and is important in the processes of cell proliferation and differentiation, and preventing the growth of cancerous tumors, p300 also mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein, p300 appears to be critical for normal development before and after birth, prompting cells to mature and assume specialized functions (differentiate), the protein functions as histone acetyltransferase that regulates transcription via chromatin remodeling, 2, E1A binding protein p300 is a protein that in humans is encoded by the EP300 gene |
| Immunogen | Human partial recombinant protein (AA 2065-2414) was used as the immunogen for this KAT3B / p300 antibody |
| Storage | Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the p300 antibody can be stored for up to one month at 4oC, After reconstitution |
| Localization | Intracellular |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24° |
| Gene target | p300 (KAT3B) |
| Short name | p300 Antibody (KAT3B) |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p300 (Antibody to) (KAT3B) |
| Alternative technique | antibodies |
| Identity | 3373 |
| Gene | EP300 |
| Long gene name | E1A binding protein p300 |
| Synonyms | p300 KAT3B |
| Synonyms name | histone acetyltransferase p300 |
| Locus | 22q13, 2 |
| Discovery year | 1998-07-31 |
| GenBank acession | U01877 |
| Entrez gene record | 2033 |
| Pubmed identfication | 7523245 |
| RefSeq identity | NM_001429 |
| Classification | Zinc fingers ZZ-type Lysine acetyltransferases |
| Havana BLAST/BLAT | OTTHUMG00000150937 |
| Locus Specific Databases | LOVD - Leiden Open Variation Database |