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P38 MAPK (Thr180) Antibody

P38 MAPK (Thr180) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long nameP38 MAPK (Thr180) Primary Polyclonal Antibody
Also known asP38 MAPK (Thr180) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenP38 MAPK Thr180
SpecificityThis is a highly specific antibody against P38 MAPK Thr180
Modification(s)Phosphorylation
Modification site(s)Thr180
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human MAPK14 around the phosphorylation site of Thr180
Gene ID number1432
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Cdc25B, Cdc25C and binds to the kinase interaction domain in the protein tyrosine phosphatase PTPRR, Downstream targets of p38 include the transcription factors ELK1 and ATF2 and the kinases MAPKAPK2 and MAPKAPK5, Dual phosphorylation by MAP2K3 and MAP2K6 is required for activation of p38 MAPK, It interacts with MAX, It is activated by environmental stress, gene knock out studies have also revealed a critical role for p38 in cardiac remodeling, many proinflammatory cytokines and lipopolysaccharide, p38 MAPK plays a critical role in the initiation of G2 delay after ultraviolet radiation, p38 MAPK plays a role in the production of IL6 and is thought to stabilize erythropoietin production during hypoxic stress, this interaction retains p38 MAPK in the cytoplasm, within the activation loop, p38 is a 38 kDa Stress Activated Protein Kinase/Map Kinase (SAPK/MAPK) that is fully activated by dual phosphorylation on threonine 180 and tyrosine 182
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names CSAID Binding Protein 1, CSAID binding protein, CSAID-binding protein, CSBP, CSBP 1, CSBP 2, CSBP1, CSBP2, CSPB 1, CSPB1, Csaids binding protein, Cytokine suppressive anti inflammatory drug binding protein, Cytokine suppressive anti-inflammatory drug-binding protein, EXIP, MAP kinase 14, MAP kinase MXI2, MAP kinase p38 alpha, MAPK 14, MAPK14, MAX interacting protein 2, MAX-interacting protein 2, MK14_HUMAN, Mitogen Activated Protein Kinase 14, Mitogen activated protein kinase p38 alpha, Mitogen-activated protein kinase 14, Mitogen-activated protein kinase p38 alpha, Mxi 2, Mxi2, PRKM14, PRKM15, RK, SAPK 2A, SAPK2A, Stress Activated Protein Kinase 2A, p38, p38 ALPHA, p38 MAP kinase, p38 MAPK, p38 mitogen activated protein kinase, p38ALPHA, p38alpha Exip, MAPK14phospho T180
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetP38 MAPK (Thr180)
Short nameP38 MAPK (Thr180) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative nameP38 MAPK (Thr180) (Antibody to)
Alternative techniqueantibodies
Identity 1189
Gene AHSA1
Long gene name activator of HSP90 ATPase activity 1
Synonyms gene C14orf3
Synonyms gene name activator of heat shock 90kDa protein ATPase homolog 1 (yeast) , chromosome 14 open reading frame 3 AHA1
Synonyms p38 Aha1 hAha1
Locus 14q24, 3
Discovery year 1999-07-01
GenBank acession AJ243310
Entrez gene record 10598
Pubmed identfication 26796264
RefSeq identity NM_012111
Havana BLAST/BLAT OTTHUMG00000171539

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