Name : p53 DINP1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN5640625634
| Long name | p53 DINP1 Primary Polyclonal Antibody |
| Also known as | p53 DINP1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | p53 DINP1 |
| Specificity | This is a highly specific antibody against p53 DINP1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p53 DINP1 |
| Gene ID number | 94241 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | Acts as a positive regulator of autophagy, Acts as a tumor suppressor by inducing cell death by an autophagy and caspase-dependent mechanism, Acts as an antioxidant and plays a major role in p53/TP53-driven oxidative stress response, Can reduce cell migration by regulating the expression of SPARC, GABARAPL1/L2, In response to cellular stress or activation of autophagy, In response to double-strand DNA breaks, MAP1LC3A/B/C and regulates autophagy, Positively regulates p53/TP53 and p73/TP73 and stimulates their capacity to induce apoptosis and regulate cell cycle, Possesses both a p53/TP53-independent intracellular reactive oxygen species (ROS) regulatory function and a p53/TP53-dependent transcription regulatory function, promotes p53/TP53 phosphorylation on 'Ser-46' and subsequent apoptosis, relocates to autophagosomes where it interacts with autophagosome-associated proteins GABARAP, Antiproliferative and proapoptotic protein involved in cell stress response which acts as a dual regulator of transcription and autophagy |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | P53DINP1, SIP, TP53INP1, Tumor protein p53-inducible nuclear protein 1 |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p53 DINP1 |
| Short name | p53 DINP1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | p53 DINP1 (Antibody to) |
| Alternative technique | antibodies |