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p53 (FL-393) Antibody, Biotin Conjugated

p53 (FL-393) Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, p53 (FL-393) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target Antigenp53 FL-393
SpecificityThis is a highly specific antibody against p53 FL-393
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceFull length human p53 protein
Gene ID number7157
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background MDM2, MDM2 is an E3 ubiquitin ligase that is upregulated in the presence of active p53, Mutations in the DNA-binding domain (DBD) of p53, a DNA-binding, amino acids 110-286, and cell cycle control mechanisms, can compromise energetically-favorable association with cis elements and are implicated in several human cancers, cell differentiation, including phosphorylation and acetylation, oligomerization domain- and transcription activation domain-containing tumor suppressor, p53 fluctuates between latent and active DNA-binding conformations and is differentially activated through posttranslational modifications, p53 localizes to the nucleus, thereby influencing programmed cell death, upregulates growth arrest and apoptosis-related genes in response to stress signals, where it poly-ubiquitinates p53 for proteasome targeting, yet can be chaperoned to the cytoplasm by the negative regulator, p53
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms Phosphoprotein p53, TP53, TRP53, Transformation related protein 53, Tumor protein p53, Tumour Protein p53, p53, p53 Cellular Tumor Antigen, p53 Tumor Suppressor, LFS1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetp53 (FL-393) Conjugated
Short name Conjugated, p53 (FL-393) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, p53 (FL-393) (Antibody to)
Alternative techniqueantibodies

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