Name : P53(Ser376) Antibody, ALEXA FLUOR 647
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :350
SKU : GEN2681998024
| Long name | ALEXA FLUOR 647 Conjugated, P53(Ser376) Polyclonal Antibody |
| Also known as | Anti-P53 Ser376 PAb ALEXA FLUOR 647 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 647, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | P53 Ser376 |
| Specificity | This is a highly specific antibody against P53 Ser376 |
| Modification | Phosphorylation |
| Modification Site | Ser376 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human P53 around the phosphorylation site of Ser376 |
| Gene ID Number | 7157 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | 20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 650nm/665nm |
| Synonyms | p53 LFS1 |
| Properties | ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode, ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 633 is a practical alternative to APC as well as Cy5, Bioss Primary Conjugated Antibodies, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is detected in the FL4 detector of the core's upgraded 2-laser FACScans, Like other Alexa Fluor dyes, exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy, the P53(Ser376) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | ALEXA FLUOR 647, Alexa Fluor |
| Gene target | P53(Ser376) |
| Short name | P53(Ser376) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 647 |
| Alternative name | ALEXA FLUOR 647, P53(Ser376) (Antibody to) |
| Alternative technique | antibodies |
| Identity | 11998 |
| Gene | TP53 |
| Long gene name | tumor protein p53 |
| Synonyms name | Li-Fraumeni syndrome |
| Locus | 17p13, 1 |
| Discovery year | 1986-01-01 |
| GenBank acession | AF307851 |
| Entrez gene record | 7157 |
| Pubmed identfication | 6396087 3456488 2047879 |
| RefSeq identity | NM_000546 |
| Havana BLAST/BLAT | OTTHUMG00000162125 |
| Locus Specific Databases | IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321 |