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P53(wt-p53) (D2F7) Antibody, Biotin Conjugated

P53(wt-p53) (D2F7) Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, P53(wt-p53) (D2F7) Monoclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismMouse (Mus musculus)
Target AntigenP53wt-p53
SpecificityThis is a highly specific antibody against P53wt-p53
ModificationUnmodified
Modification siteNone
ClonalityMonoclonal
CloneD2F7
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human P53(wt-p53)
Gene ID number7157
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 20937277), Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms, DNA binding, DNA repair, Feb 2013], Mutations in this gene are associated with a variety of human cancers, The encoded protein responds to diverse cellular stresses to regulate expression of target genes, [provided by RefSeq, and oligomerization domains, apoptosis, including hereditary cancers such as Li-Fraumeni syndrome, or changes in metabolism, senescence, thereby inducing cell cycle arrest, This gene encodes a tumor suppressor protein containing transcriptional activation
Purification methodPurified by Protein G
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms p53 LFS1
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetP53(wt-p53) (D2F7) Conjugated
Short name Conjugated, P53(wt-p53) (D2F7) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, P53(wt-p53) (D2F7) (Antibody to)
Alternative techniqueantibodies
Identity 11998
Gene TP53
Long gene name tumor protein p53
Synonyms name Li-Fraumeni syndrome
Locus 17p13, 1
Discovery year 1986-01-01
GenBank acession AF307851
Entrez gene record 7157
Pubmed identfication 6396087 3456488 2047879
RefSeq identity NM_000546
Havana BLAST/BLAT OTTHUMG00000162125
Locus Specific Databases IARC TP53 Mutation Database p53 UMD TP53 mutation database Database of Germline p53 Mutations MUTP53LOAD, Mutant p53 Loss Of Activity Database LRG_321

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