Name : p63 Antibody, ALEXA FLUOR 488
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES
Price :332
SKU : GEN2792856170
| Long name | ALEXA FLUOR 488 Conjugated, p63 Polyclonal Antibody |
| Also known as | Anti-p63 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | p63 |
| Specificity | This is a highly specific antibody against p63 |
| Modification | Unmodified |
| Modification Site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 370-420/680 |
| Subcellular location | Nucleus |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p63 protein |
| Gene ID Number | 8626 |
| Swiss Prot | Q9H3D4 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | Activates transcription of the p21 promoter, Involved in Notch signaling by probably inducing JAG1 and JAG2, Isoform 2 activates RIPK4 transcription, May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes, Plays a role in the regulation of epithelial morphogenesis, Required for limb formation from the apical ectodermal ridge, The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity, The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm, Acts as a sequence specific DNA binding transcriptional activator or repressor |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the p63 Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | p63 |
| Short name | p63 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, p63 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 52353 |
| Gene | TPRG1LP1 |
| Long gene name | tumor protein p63 regulated 1 like pseudogene 1 |
| Locus | 19q13, 43 |
| Discovery year | 2016-07-28 |
| Entrez gene record | 100130490 |