Name : p73(Tyr99) Antibody, Cy5 Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :368
SKU : GEN4027147886
| Long name | Cy5 Conjugated, p73(Tyr99) Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | 5, Cy5 |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | p73 Tyr99 |
| Specificity | This is a highly specific antibody against p73 Tyr99 |
| Modification | Phosphorylation |
| Modification site | Tyr99 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human p73 around the phosphorylation site of Tyr99 [SP(p-Y)AQ] |
| Gene ID number | 7161 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Alternative splicing of the proto-oncogene H-ras pre-mRNA has led to two distinct transcripts, However, In this study, In this study, Oncogenic MDM2 (mouse double minutes 2) is a known repressor of p73 transcriptional activity, Ras proteins are known to be small membrane-localized guanine nucleotide-binding proteins, The p73 protein, Therefore, a tumor suppressor gene, by the yeast two-hybrid screening method, involving p19ras and p73, it further inhibited the association of MDM2 to the p73 protein, p19ras, p19ras is localized in the nucleus and the cytosol and its interaction with P73 protein occurred exclusively in the nucleus, this study presents a novel pathway of Ras signaling that occurs in the nucleus, unlike other Ras proteins, when p19ras was bound to MDM2, P73 protein is a structural and functional homologue of p53 |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 625, 650nm/670nm |
| Synonyms | P73_HUMAN, TP 73, TP73, TP73phospho Y99, Tumor Protein p73, p53 Related Protein, p53 like transcription factor, p73, p73Tyr99 |
| Properties | Cy5 antibodies are excited by the 650-nanometer wave of an argon laser and detected at a 670-nanometer captor, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | p73(Tyr99) Conjugated |
| Short name | Conjugated, p73(Tyr99) Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Cy5 |
| Alternative name | cyanine 5 coupled, p73(Tyr99) (Antibody to) |
| Alternative technique | antibodies |