| Alternative name1 | Anti-Rabbit Polyclonal (IgG) to Human APC |
| Alternative name2 | Rabbit PAb (IgG) to Human APC |
| Alternative name3 | Lapin Polyclonal (IgG) to Homo sapiens APC |
| Alternative name4 | APC |
| Alternative name5 | APC, Adenomatosis polyposis coli, Adenomatous polyposis coli, BTPS2, DP2, DP2, DP3, Deleted in polyposis 2, FPC, GS, Human APC, PPP1R46, Protein APC, 5, 5, Anti-APC Antibody (aa2794-2843) IHC-plus |
| Other names | Adenomatous polyposis coli protein, Deleted in polyposis 2, adenomatosis polyposis coli tumor suppressor, adenomatous polyposis coli, adenomatous polyposis coli protein, deleted in polyposis 2, protein phosphatase 1, regulatory subunit 46, 5, 5, adenomatous polyposis coli protein isoform b |
| Gene name | APC |
| Gene name synonims | N/A |
| Other gene names | APC, BTPS2, DP2, DP2, DP2, DP3, GS, PPP1R46, Protein APC, 5, 5, APC |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Mouse, Rat, Human |
| Specificity and cross-reactivity | APC Antibody detects endogenous levels of total APC protein |
| Purification method | Immunoaffinity Purified |
| Form/Appearance | 0, 150 mM sodium chloride, 50% glycerol, Ca2+), pH 7, 02% sodium azide, 4, PBS (without Mg2+ |
| Concentration | 1 miligram per 1 mililiter |
| Storage and shipping | for up to one year, Store productone should be stored at -20 degrees Celsius |
| Tested for: | ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | Depending on the epitopes used human ELISA kits can be cross reactive to many other species, Human proteins, Mainly analyzed are human serum, Modern , cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies, human cell culture supernatants and biological samples, plasma, primarily , saliva, urine, , (Homo sapiens, C, C for long term storage and for short term at + 5°, Homo sapiens sapiens), If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24°, humans , ssp |
| About | 2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Gene target | PAb APC |
| Short name | PAb (IgG) APC Antibody |
| Technique | IgGs, antibodies against human proteins, antibodies for, Antibody |
| Isotype | IgG |
| Label | APC |
| Species | Humans, Human |
| Alternative name | sapiens adenomatous polyposis coli (Antibody to), polyclonal (Immunoglobulin G) to H |
| Alternative technique | antibodies |
| Alternative to gene target | APC and IDBG-37007 and ENSG00000134982 and 324, Apc and IDBG-134573 and ENSMUSG00000005871 and 11789, BT, BTPS2 and DP2 and DP2, microtubule plus-end binding, nuclei, this GO :0000281 and mitotic cytokinesis and biological process this GO :0000776 and kinetochore and cellular component this GO :0001822 and kidney development and biological process this GO :0001942 and hair follicle development and biological process this GO :0005488 and binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005813 and centrosome and cellular component this GO :0005829 and cytosol and cellular component this GO :0005881 and cytoplasmic microtubule and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005913 and cell-cell adherens junction and cellular component this GO :0005923 and tight junction and cellular component this GO :0006461 and protein complex assembly and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0006974 and cellular response to DNA damage stimulus and biological process this GO :0007026 and negative regulation of microtubule depolymerization and biological process this GO :0007050 and cell cycle arrest and biological process this GO :0007091 and metaphase/anaphase transition of mitotic cell cycle and biological process this GO :0007094 and mitotic spindle assembly checkpoint and biological process this GO :0007155 and cell adhesion and biological process this GO :0007389 and pattern specification process and biological process this GO :0007409 and axonogenesis and biological process this GO :0008013 and beta-catenin binding and molecular function this GO :0008017 and microtubule binding and molecular function this GO :0008285 and negative regulation of cell proliferation and biological process this GO :0009798 and axis specification and biological process this GO :0009952 and anterior/posterior pattern specification and biological process this GO :0009953 and dorsal/ventral pattern formation and biological process this GO :0009954 and proximal/distal pattern formation and biological process this GO :0016055 and Wnt signaling pathway and biological process this GO :0016328 and lateral plasma membrane and cellular component this GO :0016477 and cell migration and biological process this GO :0019827 and stem cell maintenance and biological process this GO :0019887 and protein kinase regulator activity and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0030027 and lamellipodium and cellular component this GO :0030178 and negative regulation of Wnt signaling pathway and biological process this GO :0030334 and regulation of cell migration and biological process this GO :0030335 and positive regulation of cell migration and biological process this GO :0030424 and axon and cellular component this GO :0030426 and growth cone and cellular component this GO :0030856 and regulation of epithelial cell differentiation and biological process this GO :0030858 and positive regulation of epithelial cell differentiation and biological process this GO :0030877 and beta-catenin destruction complex and cellular component this GO :0031116 and positive regulation of microtubule polymerization and biological process this GO :0031122 and cytoplasmic microtubule organization and biological process this GO :0031253 and cell projection membrane and cellular component this GO :0031274 and positive regulation of pseudopodium assembly and biological process this GO :0032587 and ruffle membrane and cellular component this GO :0032886 and regulation of microtubule-based process and biological process this GO :0033077 and T cell differentiation in thymus and biological process this GO :0035019 and somatic stem cell maintenance and biological process this GO :0035371 and microtubule plus-end and cellular component this GO :0042483 and negative regulation of odontogenesis and biological process this GO :0042995 and cell projection and cellular component this GO :0043065 and positive regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0043409 and negative regulation of MAPK cascade and biological process this GO :0043588 and skin development and biological process this GO :0044295 and axonal growth cone and cellular component this GO :0044336 and canonical Wnt signaling pathway involved in negative regulation of apoptotic process and biological process this GO :0044337 and canonical Wnt signaling pathway involved in positive regulation of apoptotic process and biological process this GO :0045295 and gamma-catenin binding and molecular function this GO :0045595 and regulation of cell differentiation and biological process this GO :0045597 and positive regulation of cell differentiation and biological process this GO :0045667 and regulation of osteoblast differentiation and biological process this GO :0045670 and regulation of osteoclast differentiation and biological process this GO :0045732 and positive regulation of protein catabolic process and biological process this GO :0045736 and negative regulation of cyclin-dependent protein serine/threonine kinase activity and biological process this GO :0045785 and positive regulation of cell adhesion and biological process this GO :0046716 and muscle cell cellular homeostasis and biological process this GO :0048538 and thymus development and biological process this GO :0050680 and negative regulation of epithelial cell proliferation and biological process this GO :0051010 and microtubule plus-end binding and molecular function this GO :0051171 and regulation of nitrogen compound metabolic process and biological process this GO :0051276 and chromosome organization and biological process this GO :0051726 and regulation of cell cycle and biological process this GO :0051781 and positive regulation of cell division and biological process this GO :0051988 and regulation of attachment of spindle microtubules to kinetochore and biological process this GO :0060041 and retina development in camera-type eye and biological process this GO :0060070 and canonical Wnt signaling pathway and biological process this GO :0060770 and negative regulation of epithelial cell proliferation involved in prostate gland development and biological process this GO :0070830 and tight junction assembly and biological process this GO :0090090 and negative regulation of canonical Wnt signaling pathway and biological process, this GO :0005488: binding, this GO :0005488: binding and also this GO :0005515: protein binding and also this GO :0008013: beta-catenin binding and also this GO :0008017: microtubule binding and also this GO :0019887: protein kinase regulator activity and also this GO :0019901: protein kinase binding and also this GO :0045295: gamma-catenin binding and also this GO :0051010: microtubule plus-end binding, this GO :0005515: protein binding, this GO :0008013: beta-catenin binding, this GO :0008017: microtubule binding, this GO :0019887: protein kinase regulator activity, this GO :0019901: protein kinase binding, this GO :0045295: gamma-catenin binding, this GO :0051010: microtubule plus-end binding, 25770 and IDBG-644937 and ENSBTAG00000018852 and 533233, 5 and DP3 and GS and PPP1R46, adenomatous polyposis coli |
| Identity | 583 |
| Gene | APC |
| Long gene name | APC, WNT signaling pathway regulator |
| Synonyms gene name | adenomatosis polyposis coli adenomatous polyposis coli |
| Synonyms | DP2 DP3 DP2, 5 PPP1R46 |
| Synonyms name | protein phosphatase 1, regulatory subunit 46 |
| Locus | 5q22, 2 |
| Discovery year | 1986-01-01 |
| GenBank acession | M74088 |
| Entrez gene record | 324 |
| Pubmed identfication | 1651563 |
| RefSeq identity | NM_000038 |
| Classification | Protein phosphatase 1 regulatory subunits Armadillo repeat containing |
| Havana BLAST/BLAT | OTTHUMG00000128806 |
| Locus Specific Databases | Adenomatous polyposis coli mutation database UMD Locus Specific Databases Colon cancer gene variant databases APC database at LOVD-China LOVD - Leiden Open Variation Database LRG_130 |
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