| Alternative name1 | Anti-Rabbit Polyclonal (IgG) to Mouse LDLR / LDL Receptor |
| Alternative name2 | Rabbit PAb (IgG) to Murine LDLR / LDL Receptor |
| Alternative name3 | Lapin Polyclonal (IgG) to Mus musculus LDLR / LDL Receptor |
| Alternative name4 | LDLR / LDL Receptor |
| Alternative name5 | FHC, LDL Receptor, LDL receptor, LDLCQ2, LDLR, Mouse LDLR, Anti-LDLR / LDL Receptor Antibody (aa499-511) IHC-plus |
| Other names | LDL receptor, Low-density lipoprotein receptor, N/A, low density lipoprotein receptor, low-density lipoprotein receptor, low-density lipoprotein receptor class A domain-containing protein 3, low-density lipoprotein receptor isoform 1 |
| Gene name | LDLR |
| Gene name synonims | N/A |
| Other gene names | FH, FHC, LDL receptor, LDLCQ2, LDLR, LDLR |
| Category | Antibodies |
| Clonality | Polyclonal |
| Immunoglobulin isotype | IgG |
| Clone | Polyclonal antibody |
| Host organism | Rabbit |
| Species reactivity | Bovine, Monkey, Mouse <, Pig (at least 90% immunogen sequence identity), Rat, /b>, Gibbon, Human, Predicted Reactivity: <, b> |
| Specificity and cross-reactivity | Synthetic peptide from murine LDL receptor amino acids 499-511 (SVADTKGVKRRTL) |
| Purification method | Affinity Purified |
| Form/Appearance | 5mg/ml BSA, pH 7, 4, Lyophilized from TBS |
| Concentration | N/A |
| Storage and shipping | Avoid repeat freeze-thaw cycles, Short term: +Store productone at +4 degrees Celsius, Long term: Store productone at -20 degrees Celsius |
| Tested for: | Immunocytochemistry (ICC), Western Blot (WB), Immunohistochemistry (IHC - Paraffin) |
| Description | Polyclonal antibodies generally are more stable and retain their reactivity under unfavorable conditions, Polyclonal antibodies have series of advantages - larger batches can be supplied at a time, Properly used, To obtain more detailed information on productone, please, refer to the full product datasheet, the time needed for production is considerably shorter, they are inexpensive to manufacture and respectively to buy, this antibody will ensure excellent and reproducible results with guaranteed success for the applications that it is tested in, productone is a polyclonal antibody of high purity and binding affinity for the antigen that it is risen against |
| Advisory | For antibodies that are in liquid form or reconstituted lyophilized antibodies small amounts could become entrapped on the seal or the walls of the tube, Prior to use briefly centrifuge the vial to gather all the solution on the bottom, avoid cycles of freezing and thawing, please, In order to retain the quality and the affinity of productone unchanged |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by MBS Polyclonals_1 they should be stored frozen at - 24° |
| About | 2 light chains, For storage sodium azide is added or you can call us to request azide free antibody preparations, IgG, The IgG antibody has 2 , There are 2 heavy chains, These will need colder storage temperatures, They represent 70% or more of , This antibody can be antigen purified or protein A or G purified, goat polyclonal antibodies , mouse monoclonal H&, Immunoglobulin gamma, L chain clones or rabbit, antibodies, antigen , binding sites, have 4 parts, serum |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| Gene target | PAb LDLR / LDL Receptor |
| Short name | PAb (IgG) Mouse LDLR / LDL Receptor Antibody |
| Technique | IgGs, antibodies against human proteins, antibodies for, mouses, Antibody |
| Isotype | IgG |
| Species | Mouses, Mouse |
| Alternative name | polyclonal (Immunoglobulin G) to Mouse low density lipoprotein receptor / LDL Receptor (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | Cell surfaces, FH and FHC and LDLCQ2, LDLR and IDBG-28808 and ENSG00000130164 and 3949, LDLR and IDBG-643476 and ENSBTAG00000012314 and 281276, Ldlr and IDBG-141358 and ENSMUSG00000032193 and 16835, this GO :0001523 and retinoid metabolic process and biological process this GO :0001948 and glycoprotein binding and molecular function this GO :0005041 and low-density lipoprotein receptor activity and molecular function this GO :0005509 and calcium ion binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005764 and lysosome and cellular component this GO :0005768 and endosome and cellular component this GO :0005769 and early endosome and cellular component this GO :0005770 and late endosome and cellular component this GO :0005794 and this GO lgi apparatus and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005887 and integral component of plasma membrane and cellular component this GO :0005905 and coated pit and cellular component this GO :0006629 and lipid metabolic process and biological process this GO :0006897 and endocytosis and biological process this GO :0006898 and receptor-mediated endocytosis and biological process this GO :0007603 and phototransduction, this GO :0001948: glycoprotein binding, this GO :0001948: glycoprotein binding and also this GO :0005041: low-density lipoprotein receptor activity and also this GO :0005509: calcium ion binding and also this GO :0005515: protein binding and also this GO :0030169: low-density lipoprotein particle binding and also this GO :0030229: very-low-density lipoprotein particle receptor activity, this GO :0005041: low-density lipoprotein receptor activity, this GO :0005509: calcium ion binding, this GO :0005515: protein binding, this GO :0030169: low-density lipoprotein particle binding, this GO :0030229: very-low-density lipoprotein particle receptor activity, very-low-density lipoprotein particle receptor activity, visible light and biological process this GO :0008203 and cholesterol metabolic process and biological process this GO :0009897 and external side of plasma membrane and cellular component this GO :0009986 and cell surface and cellular component this GO :0010008 and endosome membrane and cellular component this GO :0010867 and positive regulation of triglyceride biosynthetic process and biological process this GO :0010899 and regulation of phosphatidylcholine catabolic process and biological process this GO :0015914 and phospholipid transport and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016032 and viral process and biological process this GO :0030169 and low-density lipoprotein particle binding and molecular function this GO :0030229 and very-low-density lipoprotein particle receptor activity and molecular function this GO :0030299 and intestinal cholesterol absorption and biological process this GO :0030301 and cholesterol transport and biological process this GO :0030669 and clathrin-coated endocytic vesicle membrane and cellular component this GO :0034362 and low-density lipoprotein particle and cellular component this GO :0034383 and low-density lipoprotein particle clearance and biological process this GO :0042157 and lipoprotein metabolic process and biological process this GO :0042159 and lipoprotein catabolic process and biological process this GO :0042632 and cholesterol homeostasis and biological process this GO :0043235 and receptor complex and cellular component this GO :0044281 and small molecule metabolic process and biological process this GO :0070508 and cholesterol import and biological process this GO :2000188 and regulation of cholesterol homeostasis and biological process, low density lipoprotein receptor |
| Identity | 6547 |
| Gene | LDLR |
| Long gene name | low density lipoprotein receptor |
| Synonyms | LDLCQ2 |
| Synonyms name | familial hypercholesterolemia |
| Locus | 19p13, 2 |
| Discovery year | 1986-01-01 |
| GenBank acession | AY114155 |
| Entrez gene record | 3949 |
| Classification | Low density lipoprotein receptors |
| Havana BLAST/BLAT | OTTHUMG00000171935 |
| Locus Specific Databases | Familial UMD Locus Specific Databases British Heart Foundation LRG_274 , Hypercholesterolemia |
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