| Alternative name 1 | Clone: 4D1, Mab anti-, PAK1 |
| Alternative name 2 | Clone: 4D1, Mab antibody-, PAK1 |
| Alternative name 3 | Clone: 4D1, Mab antibody-, PAK1 |
| Alternative name 4 | anti-PAK1 Clone: 4D1 |
| Alternative name 5 | PAK1 Clone: 4D1 |
| Clonality | Monoclonal Antibody |
| Description | Amongst the advantages of the monoclonal antibodies are: the fact that while the hybridoma takes a bit longer to be produced, If used correctly and according the protocol, in comparison to the polyclonal antibodies monoclonal antibodies are highly specific to a given epitope and can be used in applications where specific targeting is required, once the line is ready there is virtually an endless supply of these antibodie throughout time with little to no variations in recognition sites of the antigen in different batches, this antibody will provide excellent and reproducible results with guaranteed success for the tested and confirmed applications, This is a monoclonal antibody which is greatly purified and with high binding affinity for the antigen that it is risen against |
| Storage and handling | Antibodies in a liquid form can be shipped and stored for a short period of time at +4 degrees Celsius, antibodies that are lyophilized can be transported at ambient temperature and stored for short terms at +4 degrees Celsius, for long term storage (up to one year) 25-50% glycerol or ethylene glycol should be added and then the container has to be stored at -20°, for longer periods - at -20 , C, Generally |
| Advisory | For antibodies in a liquid form or reconstituted lyophilized antibodies small amounts of the soultion could be captured on the cap or the walls of the container, Right before use you could briefly centrifuge the vial to collect all of the solution on the bottom, To keep the quality and the affinity of the antibody cycles of freezing and thawing should be avoided |
| About | Each murine monoclonal anibody has his own affinity specific for the clone, Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes, Monoclonals of this antigen are available in different clones |
| Test | A/J, BALB/c, Mouse are mature after 40 days for females and 55 days for males, SCID while the CD-1 is outbred as strain, The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year, Transgenic, congenic and inbread strains are known for C57BL/6, knock-out, Mouse , mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab, or |
| Latin name | Mus musculus |
| French translation | anticorps |
| Gene target | Monoclonal 4D1, PAK1 |
| Short name | Mouse Monoclonal antibody- Clone: 4D1, PAK1 |
| Technique | Monoclonals or monoclonal antibodies, mouses, Mouse |
| Species | Mouses, Mouse |
| Alternative name | Mouse monoclonal (Antibody to)-, clonality: 4D1, p21 protein (Cdc42/Rac)-activated kinase 1 |
| Alternative technique | murine |
| Alternative to gene target | PAK1 and IDBG-642220 and ENSBTAG00000010191 and 533729, PAK1 and IDBG-65610 and ENSG00000149269 and 5058, PAKalpha, Pak1 and IDBG-199974 and ENSMUSG00000030774 and 18479, nuclei, this GO :0001666 and response to hypoxia and biological process this GO :0001726 and ruffle and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006887 and exocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007015 and actin filament organization and biological process this GO :0007411 and axon guidance and biological process this GO :0007528 and neuromuscular junction development and biological process this GO :0010033 and response to organic substance and biological process this GO :0014704 and intercalated disc and cellular component this GO :0016020 and membrane and cellular component this GO :0016358 and dendrite development and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding, transferring phosphorus-containing groups and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030018 and Z disc and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0031941 and filamentous actin and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033148 and positive regulation of intracellular estrogen receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042060 and wound healing and biological process this GO :0043113 and receptor clustering and biological process this GO :0043234 and protein complex and cellular component this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0060244 and negative regulation of cell proliferation involved in contact inhibition and biological process, p21 protein (Cdc42/Rac)-activated kinase 1 |
| Identity | 8590 |
| Gene | PAK1 |
| Long gene name | p21 (RAC1) activated kinase 1 |
| Synonyms gene name | p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) p21 protein (Cdc42/Rac)-activated kinase 1 |
| Synonyms name | STE20 homolog, yeast |
| Locus | 11q13, 1 , 5-q14 |
| Discovery year | 1997-12-05 |
| GenBank acession | U51120 |
| Entrez gene record | 5058 |
| Pubmed identfication | 8805275 9533029 |
| RefSeq identity | NM_002576 |
| Havana BLAST/BLAT | OTTHUMG00000165138 |
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