| Long name | ALEXA FLUOR 488 Conjugated, PAK1(Thr212) Polyclonal Antibody |
| Also known as | Anti-PAK1 Thr212 PAb ALEXA FLUOR 488 |
| Category | Conjugated Primary Antibodies |
| Conjugated with | 488, ALEXA FLUOR® |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PAK1 Thr212 |
| Specificity | This is a highly specific antibody against PAK1 Thr212 |
| Modification | Phosphorylation |
| Modification Site | Thr212 |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic phosphopeptide derived from human PAK1 around the phosphorylation site of Thr212 |
| Gene ID Number | 5058 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Cross-reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the antigen | CDC42 and RAC1, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, and have been implicated in a wide range of biological activities, and may play a role in regulating the apoptotic events in the dying cell, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling |
| Purification | Purified by Protein A |
| Storage conditions | 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA |
| Excitation emission | 499nm/519nm |
| Properties | ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PAK1(Thr212) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate |
| Conjugation | Alexa Fluor |
| Gene target | PAK1(Thr212) |
| Short name | PAK1(Thr212) Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Label | ALEXA FLUOR 488 |
| Alternative name | ALEXA FLUOR 488, p21 protein (Cdc42/Rac)-activated kinase 1(Thr212) (Antibody to) |
| Alternative technique | antibodies |
| Alternative to gene target | PAK1 and IDBG-642220 and ENSBTAG00000010191 and 533729, PAK1 and IDBG-65610 and ENSG00000149269 and 5058, PAKalpha, Pak1 and IDBG-199974 and ENSMUSG00000030774 and 18479, nuclei, this GO :0001666 and response to hypoxia and biological process this GO :0001726 and ruffle and cellular component this GO :0001934 and positive regulation of protein phosphorylation and biological process this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005518 and collagen binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0005911 and cell-cell junction and cellular component this GO :0005925 and focal adhesion and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006887 and exocytosis and biological process this GO :0006915 and apoptotic process and biological process this GO :0007015 and actin filament organization and biological process this GO :0007411 and axon guidance and biological process this GO :0007528 and neuromuscular junction development and biological process this GO :0010033 and response to organic substance and biological process this GO :0014704 and intercalated disc and cellular component this GO :0016020 and membrane and cellular component this GO :0016358 and dendrite development and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005518: collagen binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005518: collagen binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding, transferring phosphorus-containing groups and molecular function this GO :0019901 and protein kinase binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030018 and Z disc and cellular component this GO :0030424 and axon and cellular component this GO :0030425 and dendrite and cellular component this GO :0030426 and growth cone and cellular component this GO :0031295 and T cell costimulation and biological process this GO :0031532 and actin cytoskeleton reorganization and biological process this GO :0031941 and filamentous actin and cellular component this GO :0031965 and nuclear membrane and cellular component this GO :0032587 and ruffle membrane and cellular component this GO :0032869 and cellular response to insulin stimulus and biological process this GO :0032956 and regulation of actin cytoskeleton organization and biological process this GO :0033138 and positive regulation of peptidyl-serine phosphorylation and biological process this GO :0033148 and positive regulation of intracellular estrogen receptor signaling pathway and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0038096 and Fc-gamma receptor signaling pathway involved in pha this GO cytosis and biological process this GO :0042060 and wound healing and biological process this GO :0043113 and receptor clustering and biological process this GO :0043234 and protein complex and cellular component this GO :0043507 and positive regulation of JUN kinase activity and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048754 and branching morphogenesis of an epithelial tube and biological process this GO :0048812 and neuron projection morphogenesis and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0051496 and positive regulation of stress fiber assembly and biological process this GO :0060244 and negative regulation of cell proliferation involved in contact inhibition and biological process, p21 protein (Cdc42/Rac)-activated kinase 1 |
| Identity | 8590 |
| Gene | PAK1 |
| Long gene name | p21 (RAC1) activated kinase 1 |
| Synonyms gene name | p21/Cdc42/Rac1-activated kinase 1 (yeast Ste20-related) p21/Cdc42/Rac1-activated kinase 1 (STE20 homolog, yeast) p21 protein (Cdc42/Rac)-activated kinase 1 |
| Synonyms name | STE20 homolog, yeast |
| Locus | 11q13, 1 , 5-q14 |
| Discovery year | 1997-12-05 |
| GenBank acession | U51120 |
| Entrez gene record | 5058 |
| Pubmed identfication | 8805275 9533029 |
| RefSeq identity | NM_002576 |
| Havana BLAST/BLAT | OTTHUMG00000165138 |
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