Filters

PAK2 (Ser20) Antibody

PAK2 (Ser20) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePAK2 (Ser20) Primary Polyclonal Antibody
Also known asPAK2 (Ser20) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPAK2 Ser20
SpecificityThis is a highly specific antibody against PAK2 Ser20
Modification(s)Phosphorylation
Modification site(s)Ser20
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PAK2 around the phosphorylation site of Ser20
Gene ID number5062
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), CDC42 and RAC1, PAK 2, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, The three most common isoforms are PAK 1, These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, and PAK 3 (also known as alpha PAK, and beta PAK, and caspase mediated proteolytic cleavage, and have been implicated in a wide range of biological activities, and may play a role in regulating the apoptotic events in the dying cell, catalyzed by Cdc42, gamma PAK, interaction with Src homology 3 (SH3) domains, is required for activation of PAK, members of which are activated by small molecular weight GTPases, respectively), P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names 65-KD antibody p21-activated protein kinase I, CB422, EC 2, Gamma PAK, Kinase, PAK 2, PAK2 phospho Ser20, PAK65, PAKgamma, S6 H4 kinase, Serine threonine protein kinase PAK 2, hPAK65, p-PAK2 S20, p-PAK2 Ser20, p21 CDKN1A-activated kinase 2a, p21 activated kinase 2, p21 protein Cdc42 Rac activated kinase 2, p21 protein Cdc42/Rac-activated kinase 2, p21-activated kinase, p21CDKN1A activated kinase 2, p58, p65PAK, 1, 7, 11, PAK2 phospho S20
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPAK2 (Ser20)
Short namePAK2 (Ser20) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namep21 protein (Cdc42/Rac)-activated kinase 2 (Ser20) (Antibody to)
Alternative techniqueantibodies
Alternative to gene target PAK2 and IDBG-634020 and ENSBTAG00000047856 and 513673, PAK2 and IDBG-71333 and ENSG00000180370 and 5062, PAK65 and PAKgamma, Pak2 and IDBG-153570 and ENSMUSG00000022781 and 224105, nuclei, this GO :0004672 and protein kinase activity and molecular function this GO :0004674 and protein serine/threonine kinase activity and molecular function this GO :0004713 and protein tyrosine kinase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005524 and ATP binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0005886 and plasma membrane and cellular component this GO :0006468 and protein phosphorylation and biological process this GO :0006469 and negative regulation of protein kinase activity and biological process this GO :0006915 and apoptotic process and biological process this GO :0006921 and cellular component disassembly involved in execution phase of apoptosis and biological process this GO :0007015 and actin filament organization and biological process this GO :0007165 and signal transduction and biological process this GO :0007411 and axon guidance and biological process this GO :0016032 and viral process and biological process this GO :0016310 and phosphorylation and biological process this GO :0016772 and transferase activity, this GO :0004672: protein kinase activity, this GO :0004672: protein kinase activity and also this GO :0004674: protein serine/threonine kinase activity and also this GO :0004713: protein tyrosine kinase activity and also this GO :0005515: protein binding and also this GO :0005524: ATP binding and also this GO :0016772: transferase activity, this GO :0004674: protein serine/threonine kinase activity, this GO :0004713: protein tyrosine kinase activity, this GO :0005515: protein binding, this GO :0005524: ATP binding, this GO :0016772: transferase activity, this GO :0019901: protein kinase binding, this GO :0030296: protein tyrosine kinase activator activity, this GO :0042802: identical protein binding, transferase activity, transferring phosphorus-containing groups, transferring phosphorus-containing groups and also this GO :0019901: protein kinase binding and also this GO :0030296: protein tyrosine kinase activator activity and also this GO :0042802: identical protein binding, transferring phosphorus-containing groups and molecular function this GO :0018105 and peptidyl-serine phosphorylation and biological process this GO :0019901 and protein kinase binding and molecular function this GO :0023014 and signal transduction by phosphorylation and biological process this GO :0030296 and protein tyrosine kinase activator activity and molecular function this GO :0031295 and T cell costimulation and biological process this GO :0038095 and Fc-epsilon receptor signaling pathway and biological process this GO :0040008 and regulation of growth and biological process this GO :0042802 and identical protein binding and molecular function this GO :0042981 and regulation of apoptotic process and biological process this GO :0043066 and negative regulation of apoptotic process and biological process this GO :0045087 and innate immune response and biological process this GO :0046777 and protein autophosphorylation and biological process this GO :0048471 and perinuclear region of cytoplasm and cellular component this GO :0050690 and regulation of defense response to virus by virus and biological process this GO :0050731 and positive regulation of peptidyl-tyrosine phosphorylation and biological process this GO :0050852 and T cell receptor signaling pathway and biological process this GO :0061098 and positive regulation of protein tyrosine kinase activity and biological process this GO :2001238 and positive regulation of extrinsic apoptotic signaling pathway and biological process this GO :2001271 and negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis and biological process, p21 protein (Cdc42/Rac)-activated kinase 2
Identity 8591
Gene PAK2
Long gene name p21 (RAC1) activated kinase 2
Synonyms gene name p21 (CDKN1A)-activated kinase 2 p21 protein (Cdc42/Rac)-activated kinase 2
Synonyms PAK65 PAKgamma
Synonyms name S6/H4 kinase
Locus 3q29
Discovery year 1998-03-25
GenBank acession U24153
Entrez gene record 5062
Pubmed identfication 7744004 7618083
RefSeq identity NM_002577
Havana BLAST/BLAT OTTHUMG00000155534

Similar products

Subscribe to our Newsletter