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PAK3 (Ser139) Antibody

PAK3 (Ser139) Antibody size: 0.1ml 281

Price 281
Size 0.1ml
Long namePAK3 (Ser139) Primary Polyclonal Antibody
Also known asPAK3 (Ser139) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPAK3 Ser139
SpecificityThis is a highly specific antibody against PAK3 Ser139
Modification(s)Phosphorylation
Modification site(s)Ser139
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PAK3 around the phosphorylation site of (Ser139)
Gene ID number5063
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), CDC42 and RAC1, PAK 2, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, The three most common isoforms are PAK 1, These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, and PAK 3 (also known as alpha PAK, and beta PAK, and caspase mediated proteolytic cleavage, and have been implicated in a wide range of biological activities, and may play a role in regulating the apoptotic events in the dying cell, catalyzed by Cdc42, gamma PAK, interaction with Src homology 3 (SH3) domains, is required for activation of PAK, members of which are activated by small molecular weight GTPases, respectively), P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names Beta PAK, CDKN1A, MRX30, MRX47, Mental retardation X linked 30, OPHN3, Oligophrenin 3, PAK-3, PAK3 p21 protein Cdc42/Rac-activated kinase 3, PAK3beta, Pak65alpha, Pak65beta, Serine threonine protein kinase PAK 3, Stk4, bPAK, hPAK3, p21 CDKN1A activated kinase 3, p21 activated kinase 3, PAK3_HUMAN
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPAK3 (Ser139)
Short namePAK3 (Ser139) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePAK3 (Ser139) (Antibody to)
Alternative techniqueantibodies
Identity 8592
Gene PAK3
Long gene name p21 (RAC1) activated kinase 3
Synonyms gene MRX30 MRX47
Synonyms gene name X-linked 47 p21 (CDKN1A)-activated kinase 3 p21 protein (Cdc42/Rac)-activated kinase 3 , mental retardation
Synonyms hPAK3 bPAK
Locus Xq23
Discovery year 1998-03-25
GenBank acession AF068864
Entrez gene record 5063
Pubmed identfication 8826460 9731525
RefSeq identity NM_002578
Classification X-linked mental retardation
Havana BLAST/BLAT OTTHUMG00000022202

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