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PAK3 (Ser139) Antibody, Biotin Conjugated

PAK3 (Ser139) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PAK3 (Ser139) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPAK3 Ser139
SpecificityThis is a highly specific antibody against PAK3 Ser139
ModificationPhosphorylation
Modification siteSer139
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PAK3 around the phosphorylation site of (Ser139)
Gene ID number5063
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Autophosphorylation of serine 141 (serine 144 for PAK 1 and serine 139 PAK 3), CDC42 and RAC1, PAK 2, The PAK proteins are a family of serine/threonine kinases that serve as targets for the small GTP binding proteins, The protein encoded by this gene is activated by proteolytic cleavage during caspase-mediated apoptosis, The three most common isoforms are PAK 1, These kinases contain numerous regulatory elements that trigger diverse signaling processes such as those initiated by activated GTPases, and PAK 3 (also known as alpha PAK, and beta PAK, and caspase mediated proteolytic cleavage, and have been implicated in a wide range of biological activities, and may play a role in regulating the apoptotic events in the dying cell, catalyzed by Cdc42, gamma PAK, interaction with Src homology 3 (SH3) domains, is required for activation of PAK, members of which are activated by small molecular weight GTPases, respectively), P21-activated kinase (PAK) is actually a family of serine/threonine protein kinases, The p21 activated kinases (PAK) are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms hPAK3 bPAK
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPAK3 (Ser139) Conjugated
Short name Conjugated, PAK3 (Ser139) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PAK3 (Ser139) (Antibody to)
Alternative techniqueantibodies
Identity 8592
Gene PAK3
Long gene name p21 (RAC1) activated kinase 3
Synonyms gene MRX30 MRX47
Synonyms gene name X-linked 47 p21 (CDKN1A)-activated kinase 3 p21 protein (Cdc42/Rac)-activated kinase 3 , mental retardation
Locus Xq23
Discovery year 1998-03-25
GenBank acession AF068864
Entrez gene record 5063
Pubmed identfication 8826460 9731525
RefSeq identity NM_002578
Classification X-linked mental retardation
Havana BLAST/BLAT OTTHUMG00000022202

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