Name : pan Cytokeratin Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN2146659548
| Long name | pan Cytokeratin Primary Polyclonal Antibody |
| Also known as | pan Cytokeratin PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | pan Cytokeratin |
| Specificity | This is a highly specific antibody against pan Cytokeratin |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 170-210/644 |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human pan cytokeratin |
| Tested Applications | IF(IHC-F), IF(IHC-P), IHC-F, IHC-P |
| Recommended dilutions | IF(IHC-F)(1:50-200), IF(IHC-P)(1:50-200), IHC-F(1:100-500), IHC-P(1:100-500) |
| Cross reactivity | Mouse, Pig, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | 20 are epithelial genes and the remaining 10 are specific for trichocytes, Among them, Apart from the relatively static functions provided in terms of supporting the nucleus and providing tensile strength to the cell, Cytokeratins interact with desmosomes and hemidesmosomes, In the cytoplasm, Numerous accessory proteins are involved in the genesis and maintenance of such structure, The cytokeratins are encoded by a family encompassing 30 genes, This association between the plasma membrane and the nuclear surface provides important implications for the organization of the cytoplasm and cellular communication mechanisms, cell movement and differentiation, the cytokeratin networks undergo rapid phosphate exchanges mediated depolymerization, the keratin filaments conform a complex network which extends from the surface of the nucleus to the cell membrane, thus collaborating to cell-cell adhesion and basal cell-underlying connective tissue connection, with important implications in the more dynamic cellular processes such as mitosis and post-mitotic period, Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 2, Cytokeratins, P-CK, [cytokeratins 1, pan CK, pan-CK, wide spectrum Cytokeratin, 4, 5, 6, 7, 8, 71, 72, 75, 78], pan-cytokeratin |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | pan Cytokeratin |
| Short name | pan Cytokeratin Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | pan Cytokeratin (Antibody to) |
| Alternative technique | antibodies |