Filters

PANK2 Antibody, FITC Conjugated

PANK2 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PANK2 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPANK2
SpecificityThis is a highly specific antibody against PANK2
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PANK2
Gene ID number80025
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background All patients have the 'eye of the tiger' sign on brain MRI, Atypical forms have onset in the second decade, Classic forms present with onset in the first decade, Clinical manifestations include progressive muscle spasticity, HARP is a rare syndrome with many clinical similarities to NBIA1, Intermediate forms manifest onset in the first decade with slow progression or onset in the second decade with rapid progression, It is an autosomal recessive neurodegenerative disorder associated with iron accumulation in the brain, It is clinically classified into classic, Patients with early onset tend to also develop pigmentary retinopathy, acanthocytosis, also known as pantothenate kinase-associated neurodegeneration (PKAN) or Hallervorden-Spatz syndrome (HSS), and intellectual deterioration which progresses to severe dementia over several years, and intermediate phenotypes, and pallidal degeneration (HARP), atypical, dysarthria, dystonia, hyperreflexia, loss of independent ambulation within 15 years, maintenance of independent ambulation up to 40 years later, muscle rigidity, primarily in the basal ganglia, rapid progression, retinitis pigmentosa, slow progression, whereas those with later onset tend to also have speech disorders and psychiatric features, Defects in PANK2 are the cause of hypoprebetalipoproteinemia, Defects in PANK2 are the cause of neurodegeneration with brain iron accumulation type 1 (NBIA1)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms HSS FLJ11729 PKAN HARP
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPANK2 Conjugated
Short name FITC Conjugated, PANK2 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PANK2 (Antibody to)
Alternative techniqueantibodies
Identity 15894
Gene PANK2
Long gene name pantothenate kinase 2
Synonyms gene C20orf48 NBIA1
Synonyms gene name neurodegeneration with brain iron accumulation 1 (Hallervorden-Spatz syndrome)
Synonyms name Hallervorden-Spatz syndrome
Locus 20p13
Discovery year 2001-06-21
GenBank acession AK021791
Entrez gene record 80025
Pubmed identfication 8944032 11479594
RefSeq identity NM_024960
Havana BLAST/BLAT OTTHUMG00000031768
Locus Specific Databases LRG_1016

Similar products

Subscribe to our Newsletter