Name : PANK3 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4735646146
| Long name | Biotin Conjugated, PANK3 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PANK3 |
| Specificity | This is a highly specific antibody against PANK3 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PANK3 |
| Gene ID number | 79646 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Closely related to its family members, Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, Localized to the cytoplasm, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver, PANK3 is regulated by feedback inhibition by CoA and its thioesters, PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration, Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle, resulting in formation of 4â, the only mitochondria targeted human PANK, &euro, &trade, -phosphopantothenate, The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FLJ12899 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PANK3 Conjugated |
| Short name | Conjugated, PANK3 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, PANK3 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 19365 |
| Gene | PANK3 |
| Long gene name | pantothenate kinase 3 |
| Locus | 5q34 |
| Discovery year | 2002-10-11 |
| GenBank acession | AK022961 |
| Entrez gene record | 79646 |
| Pubmed identfication | 11479594 |
| RefSeq identity | NM_024594 |
| Havana BLAST/BLAT | OTTHUMG00000130410 |