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PANK3 Antibody, FITC Conjugated

PANK3 Antibody, FITC Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name FITC Conjugated, PANK3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPANK3
SpecificityThis is a highly specific antibody against PANK3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PANK3
Gene ID number79646
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Closely related to its family members, Coenzyme A is an important coenzyme involved in the synthesis and oxidation of fatty acids, Localized to the cytoplasm, PANK1, PANK2 and PANK4, PANK3 is highly expressed in liver, PANK3 is regulated by feedback inhibition by CoA and its thioesters, PANK3 transfers a phosphate from ATP to pantothenate (Vitamin B5), Pantothenate kinase 3 (PANK3) is a 370 amino acid member of the pantothenate kinase family that plays a role in the physiological regulation of the intracellular CoA concentration, Pantothenate kinase associated neurodegeneration (PKAN) results from mutations in the gene encoding PANK2, as well as the oxidation of pyruvate in the citric acid (Krebs) cycle, resulting in formation of 4â, the only mitochondria targeted human PANK, &euro, &trade, -phosphopantothenate, The pantothenate kinase (PANK) family of proteins catalyzes the first step in coenzyme A (CoA) biosynthesis
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms FLJ12899
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPANK3 Conjugated
Short name FITC Conjugated, PANK3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PANK3 (Antibody to)
Alternative techniqueantibodies
Identity 19365
Gene PANK3
Long gene name pantothenate kinase 3
Locus 5q34
Discovery year 2002-10-11
GenBank acession AK022961
Entrez gene record 79646
Pubmed identfication 11479594
RefSeq identity NM_024594
Havana BLAST/BLAT OTTHUMG00000130410

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