Filters

PAPP-A Antibody

PAPP-A Antibody size: 0.1mg 406

Supplier NJS POLY
Price 406
Size 0.1mg
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
CategoryAntibody
Concentration2ml sterile DI water, 5mg/ml if reconstituted with 0
FormAntigen affinity purified
ConjugationUnconjugated
ClonePolyclonal antibody
Recognised antigenPAPP-A
Host animalRabbit (Oryctolagus cuniculus)
ClonalityPolyclonal (rabbit origin)
Species reactivity Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur, Human (Homo sapiens)
Tested applications IHC-P, WB
Recommended dilutions5-1ug/ml, 5-1ug/ml, IHC (Paraffin): 0, Western blot: 0
Notes Titration of the PAPP-A antibody may be required due to differences in protocols and secondary/substrate sensitivity, The stated application concentrations are suggested starting amounts
Intented useThis PAPP-A antibodyis to be used only for research purposes and not for diagnostics
Gene ID #5069
PurityAntigen affinity
Description It has been found that circulating PAPP-A is a disulfide-bridged complex with proMBP in which the subunits of the constituents are present in a 1:1 molar ratio, It is thought to be involved in local proliferative processes such as wound healing and bone remodeling, Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses, PAPP-A is found in the ovarian follicles, This gene encodes a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs), also known as DIPLA1, and fallopian tubes of nonpregnant women and in the seminal vesicles and seminal fluid of males, follicular fluid, is a protein that in humans is encoded by the PAPPA gene, luteal cells, Pappalysin-1
ImmunogenHuman partial recombinant protein (AA 95-388) was used as the immunogen for this PAPP-A antibody
Storage Avoid repeated freezing and thawing, Celcius or lower, Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity, For long-term, Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized, aliquot and store at -20 deg, the PAPP-A antibody can be stored for up to one month at 4oC, After reconstitution
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°
Gene targetPAPP-A
Short namePAPP-A Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePAPP-A (Antibody to)
Alternative techniqueantibodies
Identity 8602
Gene PAPPA
Long gene name pappalysin 1
Synonyms gene name pappalysin 1 , pregnancy-associated plasma protein A
Synonyms PAPP-A PAPPA1 IGFBP-4ase PAPA ASBABP2 DIPLA1
Synonyms name insulin-like growth factor-dependent IGF binding protein-4 protease aspecific BCL2 ARE-binding protein 2 differentially placenta 1 expressed protein
Locus 9q33, 1
Discovery year 1992-09-25
Entrez gene record 5069
Pubmed identfication 7679961
RefSeq identity NM_002581
Classification Sushi domain containing Pappalysins
Havana BLAST/BLAT OTTHUMG00000021045

Similar products

Subscribe to our Newsletter