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PAR4 (Thr163) Antibody, ALEXA FLUOR 488

PAR4 (Thr163) Antibody, ALEXA FLUOR 488 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 488 Conjugated, PAR4 (Thr163) Polyclonal Antibody
Also known asAnti-PAR4 Thr163 PAb ALEXA FLUOR 488
CategoryConjugated Primary Antibodies
Conjugated with 488, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPAR4 Thr163
SpecificityThis is a highly specific antibody against PAR4 Thr163
ModificationPhosphorylation
Modification SiteThr163
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PAR4 around the phosphorylation site of Thr163
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen 2001), 2001), 2006), However, Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, PAR1 and PAR3 are activated by thrombin, PAR4 is expressed along with PAR1 on human platelets, The PAR family consists of 4 receptors, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al, and each plays an important role in thrombin-induced platelet aggregation (Holinstat et al, and platelets from mice lacking PAR4 fail to aggregate in response to thrombin (Sambrano et al, indicating that PAR4 is a potential target for treatment of thrombosis in humans, platelets from mice express PAR4 but not PAR1, that are activated by proteolytic cleavage of the N-terminal domain of the receptor to reveal a tethered ligand, the proteinase-activated receptors (PARs), PAR4 is a member of a unique family of GPCRs
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission499nm/519nm
Synonyms PAR4 PAR-4
Properties ALEXA FLUOR they should be stored frozen at - 24°, Alexa Fluor 488 has the same range to that of fluorescein isothiocyanate (FITC), Also Alexa Fluor 488 is pH stable, As a result of this photo stability, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, It is distinguished in the FL1 of a FACS-Calibur or FACScan, has a very high photo stability, it has turned into an antibody for fluorescent microscopy and FACS FLOW cytometry, yet the PAR4 (Thr163) Antibody, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
ConjugationAlexa Fluor
Gene targetPAR4 (Thr163)
Short namePAR4 (Thr163) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 488
Alternative name ALEXA FLUOR 488, PAR4 (Thr163) (Antibody to)
Alternative techniqueantibodies
Identity 29998
Gene PWAR4
Long gene name Prader Willi/Angelman region RNA 4
Locus 15q11, 2
Discovery year 2013-06-14
Entrez gene record 347745
Pubmed identfication 11106375 7987392

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