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PAR4 (Thr163) Antibody, Cy3 Conjugated

PAR4 (Thr163) Antibody, Cy3 Conjugated size: 0.1ml 368

Price 368
Size 0.1ml
Long name Cy3 Conjugated, PAR4 (Thr163) Polyclonal Antibody
CategoryConjugated Primary Antibodies
Conjugationcy3 conjugation kit
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPAR4 Thr163
SpecificityThis is a highly specific antibody against PAR4 Thr163
ModificationPhosphorylation
Modification siteThr163
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PAR4 around the phosphorylation site of Thr163
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background 2001), 2001), 2006), However, Mice lacking PAR4 are protected from mesenteric arteriole thrombosis, PAR1 and PAR3 are activated by thrombin, PAR4 is expressed along with PAR1 on human platelets, The PAR family consists of 4 receptors, and PAR2 and PAR4 are activated by several serine proteases (Macfarlane et al, and each plays an important role in thrombin-induced platelet aggregation (Holinstat et al, and platelets from mice lacking PAR4 fail to aggregate in response to thrombin (Sambrano et al, indicating that PAR4 is a potential target for treatment of thrombosis in humans, platelets from mice express PAR4 but not PAR1, that are activated by proteolytic cleavage of the N-terminal domain of the receptor to reveal a tethered ligand, the proteinase-activated receptors (PARs), PAR4 is a member of a unique family of GPCRs
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission512, 550nm/570, 615nm
Synonyms PAR4 PAR-4
Properties 1 of the PAR4 (Thr163) Antibody, Conjugated can be used in flow cytometry but typically shows lower fluorescence intensity comparable to that of PE or APC, Cy3 antibodies are excited by the 488-nanometer wave of an argon laser and the 633-nanometer line of a helium-neon diode laser, This Bioss Primary Conjugated Antibodies antibody is well suited for fluorescent microscopy, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPAR4 (Thr163) Conjugated
Short name Conjugated, PAR4 (Thr163) Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelCy3
Alternative name cyanine 3 coupled, PAR4 (Thr163) (Antibody to)
Alternative techniqueantibodies
Identity 29998
Gene PWAR4
Long gene name Prader Willi/Angelman region RNA 4
Locus 15q11, 2
Discovery year 2013-06-14
Entrez gene record 347745
Pubmed identfication 11106375 7987392

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