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PARK2(Ser101) Antibody

PARK2(Ser101) Antibody size: 0.1ml 281

Supplier BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price 281
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long namePARK2(Ser101) Primary Polyclonal Antibody
Also known asPARK2(Ser101) PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPARK2 Ser101
SpecificityThis is a highly specific antibody against PARK2 Ser101
Modification(s)Phosphorylation
Modification site(s)Ser101
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PARK2 around the phosphorylation site of Ser101
Gene ID number5071
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivityHuman
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin, Parkin, The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions), the second most common neurodegenerative disease after Alzheimer's Disease, thus targeting them for degradation by the proteasome, Parkinson's Disease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AR JP, E3 ubiquitin protein ligase parkin, FRA6E, LPRS 2, LPRS2, PARK 2, PARK2, PDJ, PRKN, PRKN 2, PRKN2, Parkinson disease autosomal recessive juvenile 2, Parkinson disease protein 2, Parkinson juvenile disease protein 2, Ubiquitin E3 ligase PRKN, PARK2phospho S101
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPARK2(Ser101)
Short namePARK2(Ser101) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePARK2(Ser101) (Antibody to)
Alternative techniqueantibodies
Identity 8607
Gene PARK2
Long gene name parkin RBR E3 ubiquitin protein ligase
Synonyms gene name E3 ubiquitin protein ligase (parkin) , Parkinson disease (autosomal recessive, juvenile) 2, parkin parkinson protein 2
Synonyms PDJ AR-JP parkin PRKN
Synonyms name E3 ubiquitin ligase
Locus 6q26
Discovery year 1997-08-18
Entrez gene record 5071
Pubmed identfication 9560156 9570960
Classification Parkinson disease associated genes RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000015970
Locus Specific Databases Parkinson', s disease Mutation Database

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