PARK2(Ser101) Antibody, Biotin Conjugated

PARK2(Ser101) Antibody, Biotin Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1

Price 350

Size 0.1ml

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Long name	Biotin Conjugated, PARK2(Ser101) Polyclonal Antibody
Category	Conjugated Primary Antibodies
Conjugation	Biotinylated
Host Organism	Rabbit (Oryctolagus cuniculus)
Target Antigen	PARK2 Ser101
Specificity	This is a highly specific antibody against PARK2 Ser101
Modification	Phosphorylation
Modification site	Ser101
Clonality	Polyclonal
Clone	Polyclonal antibody
Concentration	1ug per 1ul
Source	KLH conjugated synthetic phosphopeptide derived from human PARK2 around the phosphorylation site of Ser101
Gene ID number	5071
Tested applications	IHC-P, WB
Recommended dilutions	IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity	Human
Crossreactive species details	not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background	Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin, Parkin, The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions), the second most common neurodegenerative disease after Alzheimer's Disease, thus targeting them for degradation by the proteasome, Parkinson's Disease
Purification method	This antibody was purified via Protein A
Storage conditions	50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission	N/A
Synonyms	PDJ AR-JP parkin PRKN
Properties	Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene target	PARK2(Ser101) Conjugated
Short name	Conjugated, PARK2(Ser101) Antibody
Technique	antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
Label	Biotin
Alternative name	biotinilated coupled, PARK2(Ser101) (Antibody to)
Alternative technique	antibodies
Identity	8607
Gene	PARK2
Long gene name	parkin RBR E3 ubiquitin protein ligase
Synonyms gene name	E3 ubiquitin protein ligase (parkin) , Parkinson disease (autosomal recessive, juvenile) 2, parkin parkinson protein 2
Synonyms name	E3 ubiquitin ligase
Locus	6q26
Discovery year	1997-08-18
Entrez gene record	5071
Pubmed identfication	9560156 9570960
Classification	Parkinson disease associated genes RBR E3 ubiquitin ligases
Havana BLAST/BLAT	OTTHUMG00000015970
Locus Specific Databases	Parkinson', s disease Mutation Database

PARK2(Ser101) Antibody, Biotin Conjugated

PARK2(Ser101) Antibody, Biotin Conjugated size: 0.1ml 350

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