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PARK2(Ser101) Antibody, FITC Conjugated

PARK2(Ser101) Antibody, FITC Conjugated size: 0.1ml 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 350
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PARK2(Ser101) Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPARK2 Ser101
SpecificityThis is a highly specific antibody against PARK2 Ser101
ModificationPhosphorylation
Modification siteSer101
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PARK2 around the phosphorylation site of Ser101
Gene ID number5071
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin, Parkin, The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions), the second most common neurodegenerative disease after Alzheimer's Disease, thus targeting them for degradation by the proteasome, Parkinson's Disease
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PDJ AR-JP parkin PRKN
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPARK2(Ser101) Conjugated
Short name FITC Conjugated, PARK2(Ser101) Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PARK2(Ser101) (Antibody to)
Alternative techniqueantibodies
Identity 8607
Gene PARK2
Long gene name parkin RBR E3 ubiquitin protein ligase
Synonyms gene name E3 ubiquitin protein ligase (parkin) , Parkinson disease (autosomal recessive, juvenile) 2, parkin parkinson protein 2
Synonyms name E3 ubiquitin ligase
Locus 6q26
Discovery year 1997-08-18
Entrez gene record 5071
Pubmed identfication 9560156 9570960
Classification Parkinson disease associated genes RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000015970
Locus Specific Databases Parkinson', s disease Mutation Database

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