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PARK2(Ser378) Antibody, ALEXA FLUOR 555

PARK2(Ser378) Antibody, ALEXA FLUOR 555 size: 100ul 350

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES
Price 350
Size 100ul
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name ALEXA FLUOR 555 Conjugated, PARK2(Ser378) Polyclonal Antibody
Also known asAnti-PARK2 Ser378 PAb ALEXA FLUOR 555
CategoryConjugated Primary Antibodies
Conjugated with 555, ALEXA FLUOR®
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPARK2 Ser378
SpecificityThis is a highly specific antibody against PARK2 Ser378
ModificationPhosphorylation
Modification SiteSer378
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic phosphopeptide derived from human PARK2 around the phosphorylation site of Ser378
Gene ID Number5071
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Cross-reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the antigen Autosomal Recessive Juvenile Parkinsonism (AR-JP) is a recently described form of Parkinson's Disease that has been linked to a gene that codes for parkin, Parkin, The amino terminus bears sequence homology to ubiquitin while functionally it acts as a RING type ubiquitin protein ligase (E3) that coordinates the transfer of ubiquitin to substrate proteins, a 52 kDa protein, has a suggested role in the ubiquitin/proteasome pathway for protein degradation, is characterized by the loss of dopaminergic neurons and the presence of Lewy bodies (comprised of alpha synuclein and parkin inclusions), the second most common neurodegenerative disease after Alzheimer's Disease, thus targeting them for degradation by the proteasome, Parkinson's Disease
PurificationPurified by Protein A
Storage conditions 50% glycerol and 0, Keep refrigerated at 2 to 8 degrees Celcius for up to one year, 09% sodium azide, Store this antibody in aqueous buffered solution containing 1% BSA
Excitation emission553nm/568nm
Synonyms PDJ AR-JP parkin PRKN
Properties ALEXA FLUOR they should be stored frozen at - 24°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies, Very high photo stable ALEXA conjugate, C, C for long term storage and for short term at + 5°, For facs or microscopy Alexa 1 conjugate
Conjugation ALEXA FLUOR 555, Alexa Fluor
Gene targetPARK2(Ser378)
Short namePARK2(Ser378) Antibody
Technique antibodies against human proteins, antibodies for, Antibody
LabelALEXA FLUOR 555
Alternative name ALEXA FLUOR 555, PARK2(Ser378) (Antibody to)
Alternative techniqueantibodies
Identity 8607
Gene PARK2
Long gene name parkin RBR E3 ubiquitin protein ligase
Synonyms gene name E3 ubiquitin protein ligase (parkin) , Parkinson disease (autosomal recessive, juvenile) 2, parkin parkinson protein 2
Synonyms name E3 ubiquitin ligase
Locus 6q26
Discovery year 1997-08-18
Entrez gene record 5071
Pubmed identfication 9560156 9570960
Classification Parkinson disease associated genes RBR E3 ubiquitin ligases
Havana BLAST/BLAT OTTHUMG00000015970
Locus Specific Databases Parkinson', s disease Mutation Database

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