Name : PARP16 Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN4665813777
| Long name | Biotin Conjugated, PARP16 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PARP16 |
| Specificity | This is a highly specific antibody against PARP16 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PARP16 |
| Gene ID number | 54956 |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Expressed as three isoforms produced by alternative splicing, PARP proteins are implicated in a variety of diseases, PARP-16 contains one PARP catalytic domain, PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane, PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, The presence of these chains alters the function of the target protein and promotes cell survival, a process that, including cancer, leads to the formation of poly(ADPribose) chains on the protein, neurodegenerative and inflammatory disorders, thereby preventing cell death, when repeated multiple times, Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | FLJ20509 FLJ25281 pART15 |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PARP16 Conjugated |
| Short name | Conjugated, PARP16 Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, PARP16 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26040 |
| Gene | PARP16 |
| Long gene name | poly(ADP-ribose) polymerase family member 16 |
| Synonyms gene | C15orf30 |
| Synonyms gene name | chromosome 15 open reading frame 30 |
| Locus | 15q22, 31 |
| Discovery year | 2004-07-05 |
| GenBank acession | AK000516 |
| Entrez gene record | 54956 |
| Pubmed identfication | 15273990 |
| RefSeq identity | NM_017851 |
| Classification | Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT | OTTHUMG00000133138 |