Name : PARP16 Antibody, FITC Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN8561990226
| Long name | FITC Conjugated, PARP16 Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Anti-FITC Antibody |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PARP16 |
| Specificity | This is a highly specific antibody against PARP16 |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PARP16 |
| Gene ID number | 54956 |
| Tested applications | IF(IHC-P) |
| Recommended dilutions | IF(IHC-P)(1:50-200) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | Expressed as three isoforms produced by alternative splicing, PARP proteins are implicated in a variety of diseases, PARP-16 contains one PARP catalytic domain, PARP-16 is a 322 amino acid poly (ADP-ribose) polymerase protein localized to the membrane, PARPs use NAD+ as a substrate to catalytically transfer ADP-ribose residues onto protein acceptors, The PARP (poly(ADP-ribose) polymerase) proteins comprise a superfamily of enzymes that functionally modify histones and other nuclear proteins, The presence of these chains alters the function of the target protein and promotes cell survival, a process that, including cancer, leads to the formation of poly(ADPribose) chains on the protein, neurodegenerative and inflammatory disorders, thereby preventing cell death, when repeated multiple times, Poly(ADP-ribosylation) is a method of DNA damage-dependent posttranslational modification that helps to rescue injured proliferating cells from cell death |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | 494nm/518nm |
| Synonyms | FLJ20509 FLJ25281 pART15 |
| Properties | Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PARP16 Conjugated |
| Short name | FITC Conjugated, PARP16 Antibody |
| Technique | Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | FITC |
| Alternative name | fluorecein coupled, PARP16 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 26040 |
| Gene | PARP16 |
| Long gene name | poly(ADP-ribose) polymerase family member 16 |
| Synonyms gene | C15orf30 |
| Synonyms gene name | chromosome 15 open reading frame 30 |
| Locus | 15q22, 31 |
| Discovery year | 2004-07-05 |
| GenBank acession | AK000516 |
| Entrez gene record | 54956 |
| Pubmed identfication | 15273990 |
| RefSeq identity | NM_017851 |
| Classification | Poly(ADP-ribose) polymerases |
| Havana BLAST/BLAT | OTTHUMG00000133138 |