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PARP3 Antibody, FITC Conjugated

PARP3 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PARP3 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPARP3
SpecificityThis is a highly specific antibody against PARP3
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
SourceKLH conjugated synthetic peptide derived from human PARP3
Gene ID number10039
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
Crossreactivity Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Binds DNA, May be involved in the regulation of PRC2 and PRC3 complex-dependent gene silencing, May link the DNA damage surveillance network to the mitotic fidelity checkpoint, Negatively influences the G1/S cell cycle progression without interfering with centrosome duplication, This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks, also detected in pancreas, brain, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism, colon, heart and spleen, leukocytes, liver, lung, ovary, placenta, prostate and thymus, skeletal muscle, small intestine, testis, the highest levels are in the kidney, Involved in the base excision repair (BER) pathway, Tissue specificity: Widely expressed
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms ADPRT3 IRT1 hPARP-3 pADPRT-3
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPARP3 Conjugated
Short name FITC Conjugated, PARP3 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, PARP3 (Antibody to)
Alternative techniqueantibodies
Identity 273
Gene PARP3
Long gene name poly(ADP-ribose) polymerase family member 3
Synonyms gene ADPRTL3
Synonyms gene name ADP-ribosyltransferase (NAD+, poly (ADP-ribose) polymerase)-like 3
Synonyms name poly(ADP-ribose) synthetase-3 NAD+ ADP-ribosyltransferase 3 poly(ADP-ribose) polymerase 3
Locus 3p21, 2
Discovery year 1999-05-24
GenBank acession AF083068
Entrez gene record 10039
Pubmed identfication 10329013
RefSeq identity NM_005485, 4
Classification Poly(ADP-ribose) polymerases
Havana BLAST/BLAT OTTHUMG00000156931

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