Name : PATJ Antibody, Biotin Conjugated
Supplier : BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price :333
SKU : GEN3344952536
| Long name | Biotin Conjugated, PATJ Polyclonal Antibody |
| Category | Conjugated Primary Antibodies |
| Conjugation | Biotinylated |
| Host Organism | Rabbit (Oryctolagus cuniculus) |
| Target Antigen | PATJ |
| Specificity | This is a highly specific antibody against PATJ |
| Modification | Unmodified |
| Modification site | None |
| Clonality | Polyclonal |
| Clone | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Source | KLH conjugated synthetic peptide derived from human PATJ |
| Tested applications | IHC-P, WB |
| Recommended dilutions | IHC-P(1:100-500), WB(1:100-1000) |
| Crossreactivity | Mouse, Rat, Human |
| Crossreactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Antigen background | CRB1 (a transmembrane protein that plays a role in epithelial cell polarity and photoreceptor development), PATJ associates with Claudin-1, Pals-associated tight junction protein (PATJ), The PATJ/Pals1/CRB1 complex can form a tripartite tight junction in epithelial cells crucial to their integrity, Tight junctions help establish polarity in mammalian epithelia by forming a physical barrier that separates apical and basolateral membranes, all of which are found in regions of noncompact myelin: the paranodal loops, and Pals1 (a Lin-7 associated protein), gap and adherens junctions, incisures of Schmidt-Lanterman and mesaxons, is differentially localized in myelinating Schwann cells, the human homolog of Drosophila Discs Lost, The membranes of myelinating Schwann cells are joined by tight |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA |
| Excitation Emission | N/A |
| Synonyms | Cipp |
| Properties | Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PATJ Conjugated |
| Short name | Conjugated, PATJ Antibody |
| Technique | antibodies against human proteins, antibodies for, antibody Conjugates, Antibody |
| Label | Biotin |
| Alternative name | biotinilated coupled, PATJ (Antibody to) |
| Alternative technique | antibodies |
| Identity | 28881 |
| Gene | PATJ |
| Long gene name | PATJ, crumbs cell polarity complex component |
| Synonyms gene | INADL |
| Synonyms gene name | InaD-like (Drosophila) |
| Synonyms name | inactivation-no-afterpotential D-like Pals1-associated tight junction |
| Locus | 1p31, 3 |
| Discovery year | 2004-12-23 |
| GenBank acession | AB044807 |
| Entrez gene record | 10207 |
| Pubmed identfication | 9280290 11374908 |
| RefSeq identity | NM_170605 |
| Classification | Crumbs complex PDZ domain containing |
| Havana BLAST/BLAT | OTTHUMG00000008560 |