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PATZ1 Antibody

PATZ1 Antibody size: 0.1ml 263

Price 263
Size 0.1ml
Long namePATZ1 Primary Polyclonal Antibody
Also known asPATZ1 PAb
CategoryPrimary Antibodies
ConjugationUnconjugated
Target AntigenPATZ1
SpecificityThis is a highly specific antibody against PATZ1
Modification(s)None
Modification site(s)Unmodified antibody
ClonalityPolyclonal antibody
Clone numberPolyclonal antibody
Concentration1ug per 1ul
Immunogen range370-420/687
Subcellular locationNucleus
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PATZ1
Gene ID number23598
Swiss ProtQ9HBE1
Tested Applications IF(IHC-P), IHC-P, WB
Recommended dilutions IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000)
Cross reactivity Mouse, Rat, Human
Cross reactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Background of the target antigen Four alternatively spliced transcript variants are described for this gene, In small round cell sarcoma, Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, Jul 2008], Since the encoded protein has typical features of a transcription factor, The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein, This is a distinct example of an intra-chromosomal rearrangement of chromosome 22, [provided by RefSeq, and the zinc-fingers comprise the DNA binding domain, it is postulated to be a repressor of gene expression, then the hybrid is thought to be translocated (t(1, this gene is fused to EWS by a small inversion of 22q, 1, 22)(p36, The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation, q12)
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA
Synonym names AT hook-, BTB/POZ domain zinc finger transcription factor, PATZ, PATZ1, Protein kinase A RI subunit alpha-associated protein, RIAZ, ZBTB19, ZNF278, ZSG, Zinc finger and BTB domain-containing protein 19, Zinc finger protein 278, Zinc finger sarcoma gene protein, and zinc finger-containing protein 1, POZ-
PropertiesC, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°
Gene targetPATZ1
Short namePATZ1 Antibody
Technique antibodies against human proteins, antibodies for, Antibody
Alternative namePOZ (BTB) and AT hook containing zinc finger 1 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target DNA-templated and biological process this GO :0006355 and regulation of transcription, DNA-templated and biological process this GO :0007283 and spermatogenesis and biological process this GO :0008584 and male this GO nad development and biological process this GO :0010468 and regulation of gene expression and biological process this GO :0030217 and T cell differentiation and biological process this GO :0045892 and negative regulation of transcription, DNA-templated and biological process this GO :0045893 and positive regulation of transcription, DNA-templated and biological process this GO :0046872 and metal ion binding and molecular function, PATZ1 and IDBG-4572 and ENSG00000100105 and 23598, PATZ1 and IDBG-636698 and ENSBTAG00000005478 and 532416, Patz1 and IDBG-138937 and ENSMUSG00000020453 and 56218, dJ400N23 and MAZR and PATZ and RIAZ and ZBTB19 and ZNF278 and ZSG, metal ion binding, nuclei, this GO :0003677 and DNA binding and molecular function this GO :0003682 and chromatin binding and molecular function this GO :0005515 and protein binding and molecular function this GO :0005634 and nucleus and cellular component this GO :0006351 and transcription, this GO :0003677: DNA binding, this GO :0003677: DNA binding and also this GO :0003682: chromatin binding and also this GO :0005515: protein binding and also this GO :0046872: metal ion binding, this GO :0003682: chromatin binding, this GO :0005515: protein binding, this GO :0046872: metal ion binding, POZ (BTB) and AT hook containing zinc finger 1
Identity 13071
Gene PATZ1
Long gene name POZ/BTB and AT hook containing zinc finger 1
Synonyms gene ZNF278
Synonyms gene name zinc finger protein 278 POZ (BTB) and AT hook containing zinc finger 1
Synonyms MAZR dJ400N23 ZBTB19 ZSG RIAZ PATZ
Locus 22q12, 2
Discovery year 1999-10-20
GenBank acession AL096880
Entrez gene record 23598
Pubmed identfication 10591208 18241078 18401526
RefSeq identity NM_032052
Classification BTB domain containing Zinc fingers C2H2-type
Havana BLAST/BLAT OTTHUMG00000151254

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