Name : PBEF1 Antibody
Supplier : BIOSS PRIMARY UNCONJUGATED ANTIBODIES
Price :263
SKU : GEN8444508710
| Long name | PBEF1 Primary Polyclonal Antibody |
| Also known as | PBEF1 PAb |
| Category | Primary Antibodies |
| Conjugation | Unconjugated |
| Target Antigen | PBEF1 |
| Specificity | This is a highly specific antibody against PBEF1 |
| Modification(s) | None |
| Modification site(s) | Unmodified antibody |
| Clonality | Polyclonal antibody |
| Clone number | Polyclonal antibody |
| Concentration | 1ug per 1ul |
| Immunogen range | 290-340/491 |
| Subcellular location | Nucleus, Secreted, Cytoplasm |
| Source | This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBEF |
| Gene ID number | 10135 |
| Swiss Prot | P43490 |
| Tested Applications | IF(IHC-P), IHC-P, WB |
| Recommended dilutions | IF(IHC-P)(1:50-200), IHC-P(1:100-500), WB(1:100-1000) |
| Cross reactivity | Mouse, Rat, Human |
| Cross reactive species details | not every possible cross-reactivity is known, Due to limited amount of testing and knowledge |
| Background of the target antigen | It is the rate limiting component in the mammalian NAD biosynthesis pathway, NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity), Plays a role in the modulation of circadian clock function, The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, an intermediate in the biosynthesis of NAD, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma, Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide |
| Purification method | This antibody was purified via Protein A |
| Storage conditions | 50% glycerol and 0, Store at -20°, 09% sodium azide, C for up to 1 year, Keep the antibody in aqueous buffered solution containing 1% BSA |
| Synonym names | 1110035O14Rik, NAmPRTase, Nampt, Nicotinamide phosphoribosyltransferase, PBEF, PBEF1, Pre-B cell-enhancing factor, Pre-B-cell colony-enhancing factor 1, VISFATIN, VF |
| Properties | C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24° |
| Gene target | PBEF1 |
| Short name | PBEF1 Antibody |
| Technique | antibodies against human proteins, antibodies for, Antibody |
| Alternative name | PBEF1 (Antibody to) |
| Alternative technique | antibodies |
| Identity | 30092 |
| Gene | NAMPT |
| Long gene name | nicotinamide phosphoribosyltransferase |
| Synonyms gene | PBEF1 |
| Synonyms gene name | pre-B-cell colony enhancing factor 1 |
| Synonyms | PBEF |
| Synonyms name | visfatin |
| Locus | 7q22, 3 |
| Discovery year | 2004-02-02 |
| GenBank acession | U02020 |
| Entrez gene record | 10135 |
| Pubmed identfication | 8289818 |
| RefSeq identity | NM_182790 |
| Havana BLAST/BLAT | OTTHUMG00000140388 |