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PBEF1 Antibody, Biotin Conjugated

PBEF1 Antibody, Biotin Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name Biotin Conjugated, PBEF1 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPBEF1
SpecificityThis is a highly specific antibody against PBEF1
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Immunogen_range290-340/491
Subcellular location Nucleus, Secreted, Cytoplasm
SourceKLH conjugated synthetic peptide derived from human PBEF
Gene ID number10135
Swiss ProtP43490
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background It is the rate limiting component in the mammalian NAD biosynthesis pathway, NAMPT-dependent oscillatory production of NAD regulates oscillation of clock target gene expression by releasing the core clock component: CLOCK-ARNTL/BMAL1 heterodimer from NAD-dependent SIRT1-mediated suppression (By similarity), Plays a role in the modulation of circadian clock function, The secreted form behaves both as a cytokine with immunomodulating properties and an adipokine with anti-diabetic properties, an intermediate in the biosynthesis of NAD, it has no enzymatic activity, partly because of lack of activation by ATP, which has a low level in extracellular space and plasma, Catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to yield nicotinamide mononucleotide
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PBEF
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPBEF1 Conjugated
Short name Conjugated, PBEF1 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, PBEF1 (Antibody to)
Alternative techniqueantibodies
Identity 30092
Gene NAMPT
Long gene name nicotinamide phosphoribosyltransferase
Synonyms gene PBEF1
Synonyms gene name pre-B-cell colony enhancing factor 1
Synonyms name visfatin
Locus 7q22, 3
Discovery year 2004-02-02
GenBank acession U02020
Entrez gene record 10135
Pubmed identfication 8289818
RefSeq identity NM_182790
Havana BLAST/BLAT OTTHUMG00000140388

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