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PCDHB12 Antibody, FITC Conjugated

PCDHB12 Antibody, FITC Conjugated size: 0.1ml 333

Supplier BIOSS PRIMARY CONJUGATED ANTIBODIES 1
Price 333
Size 0.1ml
Contact us Ask Component cell markers and DNA bp. markers are genetic markerser genes or DNA sequenceswith selection audit
Long name FITC Conjugated, PCDHB12 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationAnti-FITC Antibody
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPCDHB12
SpecificityThis is a highly specific antibody against PCDHB12
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human PCDHB12
Tested applicationsIF(IHC-P)
Recommended dilutionsIF(IHC-P)(1:50-200)
CrossreactivityHuman
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background As a result, Localized to the cell membrane, PCDHB12 (Protocadherin beta 12) is a 795 amino acid protein that is one of 16 proteins in the protocadherin beta cluster, PCDHB12 is a single-pass type I membrane protein that contains six cadherin domains, PCDHB12 may participate in the establishment and maintenance of specific neuronal connections in the brain, There are three protocadherin gene clusters, Unlike the alpha and gamma gene clusters whose genes are spliced to downstream constant region exons during transcription, all of which contain multiple tandemly arranged genes, beta and gamma, designated alpha, each protocadherin beta gene encodes the transmembrane, extracellular and short cytoplasmic domains of the protein, members of the beta cluster (such as PCDHB12) do not use constant-region exons to produce mRNAs, Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation Emission494nm/518nm
Synonyms PCDH-BETA12
Properties Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes, FITC has a green emission that's usually collected at 530 nanometers, FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light, For fluorescent microscopy applications, This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS, When excited at 488 nanometers, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, the FL1 detector of a FACSCalibur or FACScan, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPCDHB12 Conjugated
Short name FITC Conjugated, PCDHB12 Antibody
Technique Fluorescein, antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelFITC
Alternative name fluorecein coupled, protocadherin b 12 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target PCDHB12 and IDBG-50135 and ENSG00000120328 and 56124, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005887 and integral component of plasma membrane and cellular component this GO :0007155 and cell adhesion and biological process this GO :0007156 and homophilic cell adhesion and biological process this GO :0007399 and nervous system development and biological process this GO :0016020 and membrane and cellular component, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, protocadherin beta 12
Identity 8683
Gene PCDHB12
Long gene name protocadherin beta 12
Locus 5q31, 3
Discovery year 2000-06-28
GenBank acession AF152491
Entrez gene record 56124
Pubmed identfication 10380929
RefSeq identity NM_018932
Classification Clustered protocadherins
Havana BLAST/BLAT OTTHUMG00000129620

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