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PCDHB13 Antibody, Biotin Conjugated

PCDHB13 Antibody, Biotin Conjugated size: 0.1ml 333

Price 333
Size 0.1ml
Long name Biotin Conjugated, PCDHB13 Polyclonal Antibody
CategoryConjugated Primary Antibodies
ConjugationBiotinylated
Host OrganismRabbit (Oryctolagus cuniculus)
Target AntigenPCDHB13
SpecificityThis is a highly specific antibody against PCDHB13
ModificationUnmodified
Modification siteNone
ClonalityPolyclonal
ClonePolyclonal antibody
Concentration1ug per 1ul
Subcellular locationExtracellular
SourceKLH conjugated synthetic peptide derived from human PCDHB13
Gene ID number56123
Tested applications IHC-P, WB
Recommended dilutions IHC-P(1:100-500), WB(1:100-1000)
Crossreactivity Mouse, Rat, Human
Crossreactive species details not every possible cross-reactivity is known, Due to limited amount of testing and knowledge
Antigen background Protocadherin beta 13 is a member of the protocadherin beta gene cluster, The beta cluster contains 16 genes and 3 pseudogenes, The extracellular domains interact in a homophilic manner to specify differential cell-cell connections, The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters, Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections, These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins, Unlike the alpha and gamma clusters, and protocadherins constitute a subfamily of nonclassic cadherins, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily, not sharing common 3' exons as expected, one of three related gene clusters tandemly linked on chromosome five, the transcripts from these genes are made up of only one large exon, Cadherins are calcium-dependent cell-cell adhesion molecules
Purification methodThis antibody was purified via Protein A
Storage conditions 50% glycerol and 0, Store refrigerated at 2 to 8 degrees Celcius for up to 1 year, 09% sodium azide, Keep the antibody in an aqueous buffered solution containing 1% BSA
Excitation EmissionN/A
Synonyms PCDH-BETA13
Properties Avidin and Streptavidin bind to the small biotin and are couple to HRP or AP for ELISA, Biotin conjugates can be detected by horseradish peroxidase, To break the streptavidin Biotin bond we suggest to use a 6 molar guanidine HCl solution with acidity of pH 1, alkaline phosphatase substrates or anti biotin conjugated antibodies, 6, C, C for long term storage and for short term at + 5°, If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°
Gene targetPCDHB13 Conjugated
Short name Conjugated, PCDHB13 Antibody
Technique antibodies against human proteins, antibodies for, antibody Conjugates, Antibody
LabelBiotin
Alternative name biotinilated coupled, protocadherin b 13 (Antibody to)
Alternative techniqueantibodies
Alternative to gene target PCDHB13 and IDBG-50161 and ENSG00000187372 and 56123, Plasma membranes, calcium ion binding, this GO :0005509 and calcium ion binding and molecular function this GO :0005886 and plasma membrane and cellular component this GO :0007156 and homophilic cell adhesion and biological process this GO :0007268 and synaptic transmission and biological process this GO :0007416 and synapse assembly and biological process this GO :0016020 and membrane and cellular component this GO :0016021 and integral component of membrane and cellular component this GO :0016339 and calcium-dependent cell-cell adhesion and biological process, this GO :0005509: calcium ion binding, this GO :0005509: calcium ion binding, protocadherin beta 13
Identity 8684
Gene PCDHB13
Long gene name protocadherin beta 13
Locus 5q31, 3
Discovery year 2000-06-28
GenBank acession AF152492
Entrez gene record 56123
Pubmed identfication 10380929
RefSeq identity NM_018933
Classification Clustered protocadherins
Havana BLAST/BLAT OTTHUMG00000129615

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